Dr Ligong Liu
Honorary Senior Research Fellow
Institute for Molecular Bioscience

Journal Articles
Wang, Carl J.H., Awad, Wael, Liu, Ligong, Mak, Jeffrey Y.W., Veerapen, Natacha, Illing, Patricia T., Purcell, Anthony W., Eckle, Sidonia B.G., McCluskey, James, Besra, Gurdyal S., Fairlie, David P., Rossjohn, Jamie and Le Nours, Jérôme (2022). Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1. Journal of Biological Chemistry, 298 (12) 102714, 1-12. doi: 10.1016/j.jbc.2022.102714
Wu, Chongyang, Hoang, Huy N., Hill, Timothy A., Lim, Junxian, Kok, W. Mei, Akondi, Kalyani, Liu, Ligong and Fairlie, David P. (2022). Helical structure in cyclic peptides: effect of N-methyl amides versus esters. Chemical Communications, 58 (89), 12475-12478. doi: 10.1039/d2cc05092g
Souter, Michael N.T., Awad, Wael, Li, Shihan, Pediongco, Troi J., Meehan, Bronwyn S., Meehan, Lucy J., Tian, Zehua, Zhao, Zhe, Wang, Huimeng, Nelson, Adam, Le Nours, Jérôme, Khandokar, Yogesh, Praveena, T., Wubben, Jacinta, Lin, Jie, Sullivan, Lucy C., Lovrecz, George O., Mak, Jeffrey Y.W., Liu, Ligong, Kostenko, Lyudmila, Kedzierska, Katherine, Corbett, Alexandra J., Fairlie, David P., Brooks, Andrew G., Gherardin, Nicholas A., Uldrich, Adam P., Chen, Zhenjun, Rossjohn, Jamie, Godfrey, Dale I. ... Eckle, Sidonia B.G. (2022). CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. Journal of Experimental Medicine, 219 (9) e20210828, 1-30. doi: 10.1084/jem.20210828
Hesping, Eva, Chua, Ming Jang, Pflieger, Marc, Qian, Yunan, Dong, Lilong, Bachu, Prabhakar, Liu, Ligong, Kurz, Thomas, Fisher, Gillian M., Skinner-Adams, Tina S., Reid, Robert C., Fairlie, David P., Andrews, Katherine T. and Gorse, Alain-Dominique J.P. (2022). QSAR classification models for prediction of hydroxamate histone deacetylase inhibitor activity against malaria parasites. ACS Infectious Diseases, 8 (1), 106-117. doi: 10.1021/acsinfecdis.1c00355
Mak, Jeffrey Y.W., Liu, Ligong and Fairlie, David P. (2021). Chemical modulators of mucosal associated Invariant T cells. Accounts of Chemical Research, 54 (17) acs.accounts.1c00359, 3462-3475. doi: 10.1021/acs.accounts.1c00359
Liu, Ligong, Dong, Lilong, Bourguet, Erika and Fairlie, David P. (2021). Targeting Class IIa HDACs: insights from henotypes and inhibitors. Current Medicinal Chemistry, 28 (42), 8628-8672. doi: 10.2174/0929867328666210629160647
Edmans, Matthew D., Connelley, Timothy K., Jayaraman, Siddharth, Vrettou, Christina, Vordermeier, Martin, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., Maze, Emmanuel Atangana, Chrun, Tiphany, Klenerman, Paul, Eckle, Sidonia B. G., Tchilian, Elma and Benedictus, Lindert (2021). Identification and phenotype of MAIT cells in cattle and their response to bacterial infections. Frontiers in Immunology, 12 627173, 627173. doi: 10.3389/fimmu.2021.627173
Mak, Jeffrey Y. W., Wu, Kai-Chen, Gupta, Praveer K., Barbero, Sheila, McLaughlin, Maddison G., Lucke, Andrew J., Tng, Jiahui, Lim, Junxian, Loh, Zhixuan, Sweet, Matthew J, Reid, Robert C., Liu, Ligong and Fairlie, David P. (2021). HDAC7 inhibition by phenacetyl and phenylbenzoyl hydroxamates. Journal of Medicinal Chemistry, 64 (4), 2186-2204. doi: 10.1021/acs.jmedchem.0c01967
Yu, Huifeng, Yang, Amy, Derrick, Steven, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P. and Cowley, Siobhan (2020). Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection. Scientific Reports, 10 (1) 13579, 13579. doi: 10.1038/s41598-020-70615-9
Awad, Wael, Meermeier, Erin W., Sandoval-Romero, Maria L., Le Nours, Jérôme, Worley, Aneta H., Null, Megan D., Liu, Ligong, McCluskey, James, Fairlie, David P., Lewinsohn, David M. and Rossjohn, Jamie (2020). Atypical TRAV1-2-T cell receptor recognition of the antigen-presenting molecule MR1. Journal of Biological Chemistry, 295 (42), 14445-14457. doi: 10.1074/jbc.RA120.015292
McWilliam, Hamish E. G., Mak, Jeffrey Y. W., Awad, Wael, Zorkau, Matthew, Cruz-Gomez, Sebastian, Lim, Hui Jing, Yan, Yuting, Wormald, Sam, Dagley, Laura F., Eckle, Sidonia B. G., Corbett, Alexandra J., Liu, Haiyin, Li, Shihan, Reddiex, Scott J. J., Mintern, Justine D., Liu, Ligong, McCluskey, James, Rossjohn, Jamie, Fairlie, David P. and Villadangos, Jose A. (2020). Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences, 117 (40), 1-12. doi: 10.1073/pnas.2011260117
Yu, Huifeng, Yang, Amy, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P. and Cowley, Siobhan (2020). CXCL16 stimulates antigen-induced MAIT cell accumulation but trafficking during lung infection is CXCR6-independent. Frontiers in Immunology, 11 1773, 1773. doi: 10.3389/fimmu.2020.01773
Howson, Lauren J., Awad, Wael, von Borstel, Anouk, Lim, Hui Jing, McWilliam, Hamish E. G., Sandoval-Romero, Maria L., Majumdar, Shamik, Hamzeh, Abdul Rezzak, Andrews, Thomas D., McDermott, David H., Murphy, Philip M., Le Nours, Jérôme, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Villadangos, Jose A., Cook, Matthew C., Turner, Stephen J., Davey, Martin S., Ojaimi, Samar and Rossjohn, Jamie (2020). Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science Immunology, 5 (49) 9492, eabc9492. doi: 10.1126/sciimmunol.abc9492
McSharry, Brian P., Samer, Carolyn, McWilliam, Hamish E.G., Ashley, Caroline L., Yee, Michael B., Steain, Megan, Liu, Ligong, Fairlie, David P., Kinchington, Paul R., McCluskey, James, Abendroth, Allison, Villadangos, Jose A., Rossjohn, Jamie and Slobedman, Barry (2020). Virus-mediated suppression of the antigen presentation molecule MR1. Cell Reports, 30 (9), 2948-2962.e4. doi: 10.1016/j.celrep.2020.02.017
Awad, Wael, Ler, Geraldine J. M., Xu, Weijun, Keller, Andrew N., Mak, Jeffrey Y. W., Lim, Xin Yi, Liu, Ligong, Eckle, Sidonia B. G., Le Nours, Jérôme, McCluskey, James, Corbett, Alexandra J., Fairlie, David P. and Rossjohn, Jamie (2020). The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature Immunology, 21 (4), 400-411. doi: 10.1038/s41590-020-0616-6
Yan, Juming, Allen, Stacey, McDonald, Elizabeth, Das, Indrajit, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., Meehan, Bronwyn S., Chen, Zhenjun, Corbett, Alexandra J., Varelias, Antiopi, Smyth, Mark J. and Teng, Michele W. L. (2020). MAIT cells promote tumor initiation, growth and metastases via tumor MR1. Cancer Discovery, 10 (1), 124-141. doi: 10.1158/2159-8290.cd-19-0569
Le Nours, Jerome, Gherardin, Nicholas A., Ramarathinam, Sri H., Awad, Wael, Wiede, Florian, Gully, Benjamin S., Khandokar, Yogesh, Praveena, T., Wubben, Jacinta M., Sandow, Jarrod J., Webb, Andrew I., von Borstel, Anouk, Rice, Michael T., Redmond, Samuel J., Seneviratna, Rebecca, Sandoval-Romero, Maria L., Li, Shihan, Souter, Michael N. T., Eckle, Sidonia B. G., Corbett, Alexandra J., Reid, Hugh H., Liu, Ligong, Fairlie, David P., Giles, Edward M., Westall, Glen P., Tothill, Richard W., Davey, Martin S., Berry, Richard, Tiganis, Tony ... Rossjohn, Jamie (2019). A class of gamma delta T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science, 366 (6472), 1522-1527. doi: 10.1126/science.aav3900
Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long‐range n to π* interaction secures the smallest known α‐helix in water. Angewandte Chemie, 131 (52), 19049-19053. doi: 10.1002/ange.201911277
Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long-range n to π* interaction secures the smallest known α-helix in water. Angewandte Chemie International Edition, 58 (52) ange.201911277, 18873-18877. doi: 10.1002/anie.201911277
Ler, Geraldine J. M., Xu, Weijun, Mak, Jeffrey Y. W., Liu, Ligong, Bernhardt, Paul V. and Fairlie, David P (2019). Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells. Chemistry – A European Journal, 25 (68) chem.201903732, 15594-15608. doi: 10.1002/chem.201903732
Juno, Jennifer A., Wragg, Kathleen M., Amarasena, Thakshila, Meehan, Bronwyn S., Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Eckle, Sidonia B. G. and Kent, Stephen J. (2019). MAIT cells upregulate α4β7 in response to acute simian immunodeficiency virus/simian HIV infection but are resistant to peripheral depletion in pigtail macaques. The Journal of Immunology, 202 (7), ji1801405-2120. doi: 10.4049/jimmunol.1801405
Wang, Huimeng, D’Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun (2018). MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications, 9 (1) 3350, 3350. doi: 10.1038/s41467-018-05202-8
Kjer-Nielsen, Lars, Corbett, Alexandra J., Chen, Zhenjun, Liu, Ligong, Mak, Jeffrey Y. W., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., McCluskey, James and Eckle, Sidonia B. G. (2018). An overview on the identification of MAIT cell antigens. Immunology and Cell Biology, 96 (6), 573-587. doi: 10.1111/imcb.12057
Wu, Chongyang, Hoang, Huy N, Liu, Ligong and Fairlie, David P (2018). Glucuronic acid as a helix-inducing linker in short peptides. Chemical Communications, 54 (17), 2162-2165. doi: 10.1039/c7cc09785a
D'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. (2018). Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection. Journal of Immunology, 200 (5), 1901-1916. doi: 10.4049/jimmunol.1701512
Ward, Ambber, Dong, Lilong, Harris, Jonathan M., Khanna, Kum Kum, Al-Ejeh, Fares, Fairlie, David P., Wiegmans, Adrian P. and Liu, Ligong (2017). Quinazolinone derivatives as inhibitors of homologous recombinase RAD51. Bioorganic and Medicinal Chemistry Letters, 27 (14), 3096-3100. doi: 10.1016/j.bmcl.2017.05.039
Jiang, Yuhong, Yau, Mei-Kwan, Kok, W. Mei, Lim, Junxian, Wu, Kai-Chen, Liu, Ligong, Hill, Timothy A., Suen, Jacky Y. and Fairlie, David P. (2017). Biased signaling by agonists of protease activated receptor 2. ACS Chemical Biology, 12 (5), 1217-1226. doi: 10.1021/acschembio.6b01088
Mak, Jeffrey Y. W., Xu, Weijun, Reid, Robert C., Corbett, Alexandra J., Meehan, Bronwyn S., Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong and Fairlie, David P. (2017). Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells. Nature Communications, 8 (1) 14599, 14599. doi: 10.1038/ncomms14599
Keller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie (2017). Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology, 18 (4), 402-411. doi: 10.1038/ni.3679
Cheng, Janice, Liu, Ligong, Pellicci, Daniel, Reddiex, Scott J.J., Cotton, Rachel, Cheng, Tan-Yun, Young, David, Van Rhijn, Ildiko, Moody, Branch, Rossjohn, Jamie, Fairlie, David, Godfrey, Dale and Williams, Spencer John (2017). Total synthesis of the Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition. Chemistry - A European Journal, 23 (7), 1694-1701. doi: 10.1002/chem.201605287
Chen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, S. B. G, Meehan, B. S., Jackson, D.C., Strugnell, R. A., Cao, H., Wang, N., Fairlie, David, Liu, L., Godfrey, D. I., Rossjohn, J., McCluskey, J. and Corbett, A. J. (2017). Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signal. Mucosal Immunology, 10 (1), 58-68. doi: 10.1038/mi.2016.39
Koay, Hui-Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Mackay, Laura K., Almeida, Catarina F., Russ, Brendan E., Nold-Petry, Claudia A., Nold, Marcel F., Bedoui, Sammy, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Sidonia B. G., Meehan, Bronwyn, D'Udekem, Yves, Konstantinov, Igor E., Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Chong, Mark M., Kedzierska, Katherine, Berzins, Stuart P., Belz, Gabrielle T., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Pellicci, Daniel G. (2016). A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology, 17 (11), 1300-1311. doi: 10.1038/ni.3565
Loh, Liyen, Wang, Zhongfang, Sant, Sneha, Koutsakos, Marios, Jegaskanda, Sinthujan, Corbett, Alexandra J., Liu, Ligong, Fairlie, David P., Crowe, Jane, Rossjohn, Jamie, Xu, Jianqing, Doherty, Peter C., McCluskey, James and Kedzierska, Katherine (2016). Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. Proceedings of the National Academy of Sciences, 113 (36), 10133-10138. doi: 10.1073/pnas.1610750113
McWilliam, Hamish E. G., Eckle, Sidonia B. G., Theodossis, Alex, Liu, Ligong, Chen, Zhenjun, Wubben, Jacinta M., Fairlie, David P., Strugnell, Richard A., Mintern, Justine D., McCluskey, James, Rossjohn, Jamie and Villadangos, Jose A. (2016). The intracellular pathway for the presentation of vitamin B–related antigens by the antigen-presenting molecule MR1. Nature Immunology, 17 (5), 531-537. doi: 10.1038/ni.3416
Yau, Mei-Kwan, Lim, Junxian, Liu, Ligong and Fairlie, David P. (2016). Protease activated receptor 2 (PAR2) modulators: a patent review (2010–2015). Expert Opinion on Therapeutic Patents, 26 (4), 471-483. doi: 10.1517/13543776.2016.1154540
Yau, Mei-Kwan, Liu, Ligong, Lim, Junxian, Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky Y., Vesey, David A., Reid, Robert C. and Fairlie, David P. (2016). Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. Bioorganic and Medicinal Chemistry Letters, 26 (3), 986-991. doi: 10.1016/j.bmcl.2015.12.048
Gherardin, Nicholas A., Keller, Andrew N., Woolley, Rachel E., Le Nours, Jerome, Ritchie, David S., Neeson, Paul J., Birkinshaw, Richard W., Eckle, Sidonia B. G., Waddington, John N., Liu, Ligong, Fairlie, David P., Uldrich, Adam P., Pellicci, Daniel G., McCluskey, James, Godfrey, Dale I and Rossjohn, Jamie (2016). Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition. Immunity, 44 (1), 32-45. doi: 10.1016/j.immuni.2015.12.005
Yau, Mei-Kwan, Suen, Jacky Y., Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark N., He, Yaowu, Hooper, John D., Reid, Robert C. and Fairlie, David P. (2016). Potent small agonists of protease activated receptor 2. ACS Medicinal Chemistry Letters, 7 (1), 105-110. doi: 10.1021/acsmedchemlett.5b00429
Yau, Mei-Kwan, Liu, Ligong, Suen, Jacky Y., Lim, Junxian, Lohman, Rink-Jan, Jiang, Yuhong, Cotterell, Adam J., Barry, Grant D., Mak, Jeffrey Y. W., Vesey, David A., Reid, Robert C. and Fairlie, David P. (2016). PAR2 modulators derived from GB88. ACS Medicinal Chemistry Letters, 7 (12), 1179-1184. doi: 10.1021/acsmedchemlett.6b00306
Eckle, Sidonia B.G., Corbett, Alexandra J., Keller, Andrew, Chen, Zhenjun, Godfrey, Dale I., Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Rossjohn, Jamie and McCluskey, James (2015). Recognition of Vitamin B precursors and byproducts by Mucosal Associated Invariant T cells. The Journal of Biological Chemistry, 290 (51), 30204-30211. doi: 10.1074/jbc.R115.685990
Bardou, Oliver, Menou, Awen, Francois, Charlene, Duitman, Jan Willem, von der Thusen, Jan H., Borie, Raphael, Sales, Katiuchia Uzzun, Mutze, Kathrin, Castier, Yves, Sage, Edouard, Liu, Ligong, Bugge, Thomas H., Fairlie, David P., Konigshoff, Melanie, Crestani, Bruno and Borensztain, Keren S. (2015). Membrane-anchored serine protease matriptase is a trigger of pulmonary fibrogenesis. American Journal of Respiratory and Critical Care Medicine, 193 (8), 847-860. doi: 10.1164/rccm.201502-0299OC
Xu, Weijun, Lim, Junxian, Goh, Chai-Yeen, Suen, Jacky Y., Jiang, Yuhong, Yau, Mei-Kwan, Wu, Kai-Chen, Liu, Ligong and Fairlie, David P. (2015). Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2. Journal of Chemical Information and Modeling, 55 (10), 2079-2084. doi: 10.1021/acs.jcim.5b00500
Sakala, Isaac G., Kjer-Nielsen, Lars, Eickhoff, Christopher S., Wang, Xiaoli, Blazevic, Azra, Liu, Ligong, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Fremont, David H., Hansen, Ted H. and Hoft, Daniel F. (2015). Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. The Journal of Immunology, 195 (2), 587-601. doi: 10.4049/jimmunol.1402545
Rahimpour, Azad, Koay, Hui Fern, Enders, Anselm, Clanchy, Rhiannon, Eckle, Sidonia B. G., Meehan, Bronwyn, Chen, Zhenjun, Whittle, Belinda, Liu, Ligong, Fairlie, David P., Goodnow, Chris C., McCluskey, James, Rossjohn, Jamie, Uldrich, Adam P., Pellicci, Daniel G. and Godfrey, Dale I. (2015). Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers. Journal of Experimental Medicine, 212 (7), 1095-1108. doi: 10.1084/jem.20142110
Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J. and Fairlie, David P. (2014). Cyclic penta- and hexaleucine peptides without N-methylation are orally absorbed. ACS Medicinal Chemistry Letters, 5 (10), 1148-1151. doi: 10.1021/ml5002823
Suen, J. Y., Cotterell, A., Lohman, R. J., Lim, J., Han, A., Yau, M. K., Liu, L., Cooper, M. A., Vesey, D. A. and Fairlie, D. P. (2014). Pathway-selective antagonism of proteinase activated receptor 2. British Journal of Pharmacology, 171 (17), 4112-4124. doi: 10.1111/bph.12757
Eckle, Sidonia B.G., Birkinshaw, Richard W., Kostenko, Lyudmila, Corbett, Alexandra J., McWilliam, Hamish E. G., Reantragoon, Rangsima, Chen, Zhenjun, Gherardin, Nicholas A., Beddoe, Travis, Liu, Ligong, Patel, Onisha, Meehan, Bronwyn, Fairlie, David P., Villadangos, Jose A., Godfrey, Dale I., Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie (2014). A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. Journal of Experimental Medicine, 211 (8), 1585-1600. doi: 10.1084/jem.20140484
Corbett, Alexandra J., Eckle, Sidonia B. G., Birkinshaw, Richard W., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y. W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie and McClusky, James (2014). T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature, 509 (7500), 361-365. doi: 10.1038/nature13160
Yau, Mei-Kwan, Liu, L.igong and Fairlie, David P. (2013). Toward drugs for protease-activated receptor 2 (PAR2). Journal of Medicinal Chemistry, 56 (19), 7477-7497. doi: 10.1021/jm400638v
Reantragoon, Rangsima, Corbett, Alexandra J., Sakala, Isaac G., Gherardin, Nicholas A., Furness, John B., Chen, Zhenjun, Eckle, Sidonia B. G., Uldrich, Adam P., Birkinshaw, Richard W., Patel, Onisha, Kostenko, Lyudmila, Meehan, Bronwyn, Kedzierska, Katherine, Liu, Ligong, Fairlie, David P., Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James and Kjer-Nielsen, Lars (2013). Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. Journal of Experimental Medicine, 210 (11), 2305-2320. doi: 10.1084/jem.20130958
Lim, Junxian, Iyer, Abishek, Liu, Ligong, Suen, Jacky Y., Lohman, Rink-Jan, Seow, Vernon, Yau, Mei-Kwan, Brown, Lindsay and Fairlie, David P. (2013). Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism. The FASEB Journal, 27 (12), 4757-4767. doi: 10.1096/fj.13-232702
Patel, Onisha, Kjer-Nielsen, Lars, Le Nours, Jerome, Eckle, Sidonia B. G., Birkinshaw, Richard, Beddoe, Travis, Corbett, Alexandra J., Liu, Ligong, Miles, John J., Meehan, Bronwyn, Reantragoon, Rangsima, Sandoval-Romero, Maria L., Sullivan, Lucy C., Brooks, Andrew G., Chen, Zhenjun, Fairlie, David P., McCluskey, James and Rossjohn, Jamie (2013). Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications, 4 (1) 2142, 2142.1-2142.8. doi: 10.1038/ncomms3142
Vesey, David A., Suen, Jacky Y., Seow, Vernon, Lohman, Rink-Jan, Liu, Ligong, Gobe, Glenda C., Johnson, David W. and Fairlie, David P. (2013). PAR2-induced inflammatory responses in human kidney tubular epithelial cells. American Journal of Physiology - Renal Physiology, 304 (6), F737-F750. doi: 10.1152/ajprenal.00540.2012
Kjer-Nielsen, Lars, Patel, Onisha, Corbett, Alexandra J., Le Nours, Jerome, Meehan, Bronwyn, Liu, Ligong, Bhati, Mugdha, Chen, Zhenjun, Kostenko, Lyudmila, Reantragoon, Rangsima, Williamson, Nicholas A., Purcell, Anthony W., Dudek, Nadine L., McConville, Malcolm J., O'Hair, Richard A. J., Khairallah, George N., Godfrey, Dale I., Fairlie, David P., Rossjohn, Jamie and McCluskey, James (2012). MR1 presents microbial vitamin B metabolites to MAIT cells. Nature, 491 (7426), 717-725. doi: 10.1038/nature11605
Liu, Ligong, Li, Caiping, Cochran, Siska, Feder, Daniel, Guddat, Luke W. and Ferro, Vito (2012). A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. Bioorganic & Medicinal Chemistry Letters, 22 (19), 6190-6194. doi: 10.1016/j.bmcl.2012.08.001
Fairweather, Jon K., Liu, Ligong, Karoli, Tomislav and Ferro, Vito (2012). Synthesis of disaccharides containing 6-Deoxy-α-L-talose as potential heparan sulfate mimetics. Molecules, 17 (8), 9790-9802. doi: 10.3390/molecules17089790
Lohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012). An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 (7), 2877-2887. doi: 10.1096/fj.11-201004
Liu, Ligong, Li, Caiping, Cochran, Siska, Jimmink, Shane and Ferro, Vito (2012). Synthesis of a heparan sulfate mimetic library targeting FGF and VEGF via click chemistry on a monosaccharide template. ChemMedChem, 7 (7), 1267-1275. doi: 10.1002/cmdc.201200151
Ferro, Vito, Liu, Ligong, Johnstone, Ken D., Wimmer, Norbert, Karoli, Tomislav, Handley, Paul, Rowley, Jessica, Dredge, Keith, Li, Cai Ping, Hammond, Edward, Davis, Kat, Sarimaa, Laura, Harenberg, Job and Bytheway, Ian (2012). Discovery of PG545: A highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis. Journal of Medicinal Chemistry, 55 (8), 3804-3813. doi: 10.1021/jm201708h
Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012). Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 (2), 256-265. doi: 10.1124/jpet.111.187062
Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100
Abbenante, Giovanni, Becker, Bernd, Blanc, Sebastien, Clark, Chris, Condie, Glenn, Fraser, Graeme, Grathwohl, Matthias, Halliday, Judy, Henderson, Senka, Lam, Ann, Liu, Ligong, Mann, Maretta, Muldoon, Craig, Pearson, Andrew, Premraj, Rajaratnam, Ramsdale, Tracie, Rossetti, Tony, Schafer, Karl, Le Thanh, Giang, Tometzki, Gerald, Vari, Frank, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010). Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry, 53 (15), 5576-5586. doi: 10.1021/jm1002777
Said, J, Trybala, E, Andersson, E, Johnstone, K, Liu, LG, Wimmer, N, Ferro, V and Bergstrom, T (2010). Lipophile-conjugated sulfated oligosaccharides as novel microbicides against HIV-1. Antiviral Research, 86 (3), 286-295. doi: 10.1016/j.antiviral.2010.03.011
Dredge, K., Hammond, E., Davis, K., Li, C. P., Liu, L., Johnstone, K., Handley, P., Wimmer, N., Gonda, T. J., Gautam, A., Ferro, V. and Bytheway, I. (2010). The PG500 series: Novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy. Investigational New Drugs, 28 (3), 276-283. doi: 10.1007/s10637-009-9245-5
Ekblad, M, Adamiak, B, Bergstrom, T, Johnstone, KD, Karoli, T, Liu, LG, Ferro, V and Trybala, E (2010). A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus. Antiviral Research, 86 (2), 196-203. doi: 10.1016/j.antiviral.2010.02.318
Johnstone, Ken D., Karoli, Tomislav, Liu, Ligong, Dredge, Keith, Copeman, Elizabeth, Li, Cai Ping, Davis, Kat, Hammond, Edward, Bytheway, Ian, Kostewicz, Edmund, Chiu, Francis C. K., Shackleford, David M., Charman, Susan A., Charman, William N., Harenberg, Job, Gonda, Thomas J. and Ferro, Vito (2010). Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. Journal of Medicinal Chemistry, 53 (4), 1686-1699. doi: 10.1021/jm901449m
Thanh, Giang Le, Abbenante, Giovanni, Adamson, George, Becker, Bernd, Clark, Chris, Condie, Glenn, Falzun, Tania, Grathwohl, Matthias, Gupta, Praveer, Hanson, Michael, Huynh, Ngoc, Katavic, Peter, Kuipers, Krystle, Lam, Ann, Liu, Ligong, Mann, Maretta, Mason, Jeff, McKeveney, Declan, Muldoon, Craig, Pearson, Andrew, Rajaratnam, Premraj, Ryan, Sarah, Tometzki, Gerry, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wilcox, Neil, Wimmer, Norbert, Yau, Annika ... Meutermans, Wim (2010). A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. Journal of Organic Chemistry, 75 (1), 197-203. doi: 10.1021/jo9021919
Rajaratnam, Premraj, Gupta, Praveer, Katavic, Peter, Kuipers, Krystle, Huyh, Ngoc, Ryan, Sarah, Falzun, Tania, Tometzki, Gerrald B., Bornaghi, Laurent, Le Thanh, Giang, Abbenante, Giovanni, Liu, Ligong, Meutermans, Wim, Wimmer, Norbert and West, Michael L. (2010). Orthogonally Protected Monosaccharide Building Blocks for Solid Phase Production of Diversity Oriented Libraries. Australian Journal of Chemistry, 63 (4), 693-699. doi: 10.1071/CH09480
Fairweather, J.K., Karoli, T., Liu, L., Bytheway, I. and Ferro, V. (2009). Synthesis of a heparan sulfate mimetic disaccharide with a conformationally locked residue from a common intermediate. Carbohydrate Research, 344 (17), 2394-2398. doi: 10.1016/j.carres.2009.09.012
Liu, LG, Johnstone, KD, Fairweather, JK, Dredge, K and Ferro, V (2009). An improved synthetic route to the potent angiogenesis inhibitor benzyl manα(1→3)-Manα(1→3)-Manα(1→3) -Manα(1→2)-Man Hexadecasulfate. Australian Journal of Chemistry, 62 (6), 546-552. doi: 10.1071/CH09015
Liu, Ligong, Bytheway, Ian, Karoli, Tomislav, Fairweather, Jon K., Cochran, Siska, Li, Caiping and Ferro, Vito (2008). Design, synthesis, FGF-1 binding, and molecular modeling studies of conformationally flexible heparin mimetic disaccharides. Bioorganic & Medicinal Chemistry Letters, 18 (1), 344-349. doi: 10.1016/j.bmcl.2007.10.071
Ferro, Vito, Dredge, Keith, Liu, Ligong, Hammond, Edward, Bytheway, Ian, Li, Caiping, Johnstone, Ken, Karoli, Tomislav, Davis, Kat, Copeman, Elizabeth and Gautam, Anand: (2007). PI-88 and novel heparan sulfate mimetics inhibit angiogenesis. Seminars in Thrombosis and Hemostasis, 33 (5), 557-562. doi: 10.1055/s-2007-982088
Van Vliet, Liisa D., Ellis, Tom, Foley, Patrick J., Liu, Ligong, Pfeffer, Frederick M., Russell, Richard A., Warrener, Ronald N., Hollfielder, Florian and Waring, Michael J. (2007). Molecular Recognition of DNA by Rigid [n]-Polynorbornane-Derived Bifunctional Intercalators: Synthesis and Evaluation of Their Binding Properties. Journal of medicinal chemistry, 50 (10), 2326-2340. doi: 10.1021/jm0613020
Freeman, Craig, Liu, Ligong, Banwell, Martin G., Brown, Kathryn J., Bezos, Anna, Ferro, Vito and Parish, Christopher R. (2005). Use of Sulfated Linked Cyclitols as Heparan Sulfate Mimetics to Probe the Heparin/Heparan Sulfate Binding Specificity of Proteins. Journal of Biological Chemistry, 280 (10), 8842-8849. doi: 10.1074/jbc.M410769200
Karoli, Tomislav, Liu, Ligong, Fairweather, Jon K., Hammond, Edward, Li, Cai Ping, Cochran, Siska, Bergefall, Kicki, Trybala, Edward, Addison, Russell S. and Ferro, Vito (2005). Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88). Journal of Medicinal Chemistry, 48 (26), 8229-8236. doi: 10.1021/jm050618p
Liu, L., Li, C.P., Cochran, S. and Ferro, V. (2004). Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries. Bioorganic & Medicinal Chemistry Letters, 14 (9), 2221-2226. doi: 10.1016/j.bmcl.2004.02.017
Liu, LG (2003). Enantioselective synthesis of protoberberine alkaloids via (-)-sparteine-mediated asymmetric condensation-cyclisation of o-toluamide anions with 3,4-dihydroisoquinolines. Synthesis-Stuttgart (11), 1705-1706.
Liu, L., Warrener, R. N., Russell, R. A. and Tiekink, E. R. T. (2002). Crystal structure of (13S*,13aR*)-2,3-dimethoxy-13-hydroxy-13a-methyl-8-oxo-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine,C20H21NO4. Zeitschrift Fur Kristallographie-New Crystal Structures, 217 (4), 583-584. doi: 10.1524/ncrs.2002.217.jg.583
Liu, L., Warrener, R. N., Russell, R. A. and Tiekink, E. R. T. (2002). Crystal structure of (3S*,4S*)-4-hydroxy-2-(2'-methoxyethyl)-3-phenyl3,4-dihydroisoquinol-1(2H)-one,C18H19NO3. Zeitschrift Fur Kristallographie-New Crystal Structures, 217 (4), 585-586. doi: 10.1524/ncrs.2002.217.jg.585
Warrener, RN, Butler, DN, Liu, LG, Margetic, D and Russell, RA (2001). Incorporation of a molecular hinge into molecular tweezers by using tandem cycloadditions onto 5,6-dimethylenenorbornene. Chemistry-A European Journal, 7 (15), 3406-3414. doi: 10.1002/1521-3765(20010803)7:15<3406::AID-CHEM3406>3.0.CO;2-M
Liu, L, Warrener, RN, Russell, RA and Tiekink, ERT (2001). Crystal structure of dimethyl 4,5-dimethylene-15-oxahexa-cyclo-[6.6.1.1(3,6).1(10,13).0(2,7).0(9,14)]heptane heptan-1,8-dicarboxylate, C22H26O5. Zeitschrift Fur Kristallographie-New Crystal Structures, 216 (4), 533-534.
Warrener, RN, Liu, LG and Russell, RA (1998). A concise, regio and stereoselective route to fluorinated protoberberines via tandem addition-cyclisation reactions of phthalide anions with 3,4-dihydroisoquinolines. Tetrahedron, 54 (26), 7485-7496. doi: 10.1016/S0040-4020(98)00378-0
Warrener, RN, Liu, LG and Russell, RA (1997). Asymmetric synthesis of protoberberine alkaloids via a tandem nucleophilic addition and intramolecular cyclisation of a chiral o-toluamide anion with 3,4-dihydroisoquinoline. Chemical Communications, 29 (22), 2173-2174. doi: 10.1039/a706008d
Liu, LG, Zhang, T and Li, ZS (1996). Regio and stereo selective hydrogenation of 17-substituted 13 beta-ethyl-11 beta-hydroxy-gona-4,9-dien-3-ones and NMR study. Tetrahedron, 52 (12), 4495-4504. doi: 10.1016/0040-4020(96)00097-X
Liu, LG, Zhang, T and Li, ZS (1996). Design of the synthesis of steroidal 1,3,5(10),9(11)-tetraenes via isomerization of 1,3,5(10),8-isomers - Effect of the solvent system. Synthetic Communications, 26 (23), 4437-4446. doi: 10.1080/00397919608003846
Liu, LG, Zhang, T and Li, ZS (1996). Silica gel promoted selective hydrolysis of 3-methoxy-2,5(10)-diene steroids. Synthetic Communications, 26 (16), 2999-3006. doi: 10.1080/00397919608004604
Liu, LG, Su, XD and Li, ZS (1995). A Novel and Efficient Process to 13-Beta-Ethyl-Gon-4-Ene-3,11,17-Trione. Synthetic Communications, 25 (20), 3113-3124. doi: 10.1080/00397919508015460
Conference Papers
Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. 2017 ACR/ARHP Annual Meeting, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.
Mak, Jeffrey, Xu, Weijun, Reid, Robert, Corbett, Alexandra, Meehan, Bronwyn, Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong and Fairlie, David (2017). Vitamin B2 related molecules that activate T cells. 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, Washington DC, USA, 20-24 August 2017. Washington DC, USA: American Chemical Society.
Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977
Fairlie, David, Liu, Ligong, Mak, Jeffrey and Xu, Weijun (2016). T cell activation by pyrimidine derivatives. WASHINGTON: AMER CHEMICAL SOC.
McCluskey, J., Corbett, A. J., Eckle, S. B. G., Chen, Z., Wang, H., Sun, S., D'Souza, C., Kostenko, L., Reantragoon, R., Meehan, B., Birkinshaw, R. W., Liu, L., Patel, O., Mahony, J., Cao, H., Jackson, D., Williamson, N. A., Strugnell, R. A., Mak, J. Y. W., Van Sinderen, D., Fairlie, D. P., Kjer-Nielsen, L., Godfrey, D., I and Rossjohn, J. (2016). MAIT cells: Friend or Foe in recognising microbial vitamin metabolites presented by the MHC-I-related molecule MR1. International Congress of Immunology (ICI), Melbourne, Australia, August 21-26, 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
McWilliam, H., Eckle, S., Theodossis, A., Liu, L., Chen, Z., Fairlie, D., Strugnell, R., Mintern, J., McCluskey, J., Rossjohn, J. and Villadangos, J. (2016). MR1 is an endoplasmic reticulum-resident sensor of vitamin B metabolites. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016 . Weinheim, Germany: Wiley.
Keller, A. N., Eckle, S. B. G., Xu, W., Liu, L., Hughes, V. A., Mak, J., Meehan, B., Pediongco, T., Birkinshaw, R. W., Chen, Z., Wang, H., Souza, C., Kostenko, L., Corbett, A. J., Purcell, A. W., Fairlie, D. P., McCluskey, J. and Rossjohn, J. (2016). Common drugs modulate mucosal-associated invariant T cell function. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Germany: Wiley. doi: 10.1002/eji.201670200
Gherardin, N. A., Keller, A. N., Woolley, R. E., Le Nours, J., Ritchie, D. S., Neeson, P. J., Birkinshaw, R. W., Eckle, S. B., Waddington, J. N., Liu, L., Fairlie, D. P., McCluskey, J., Pellicci, D. G., Uldrich, A. P., Rossjohn, J. and Godfrey, D., I (2016). A broad family of MR1-restricted T cells. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Germany: Wiley.
Godfrey, D., Koay, H. -F, Gherardin, N., Enders, A., Loh, L., Chen, Z., Corbett, A., Eckle, S., Meehan, B., d'Udekem, Y., Konstantinov, I, Lappas, M., Liu, L., Goodnow, C., Fairlie, D., Rossjohn, J., Kedzierska, K., Berzins, S., McCluskey, J., Uldrich, A. and Pellicci, D. (2016). Thymic precursors to the mucosal-associated invariant T cell lineage. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. HOBOKEN: WILEY-BLACKWELL.
Eckle, S. B. G., Keller, A. N., Xu, W., Meehan, B., Pediongco, T., Liu, L., Hughes, V. A., Mak, J. Y. W., Birkinshaw, R. W., Chen, Z., Wang, H., D'Souza, C., Kostenko, L., Corbett, A. J., Purcell, A. W., Fairlie, D. P., Rossjohn, J. and McCluskey, J. (2016). Drugs/drug analogues modulate MAIT cell function in an MR1-dependent manner. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200
Birkinshaw, Richard W., Corbetta, Alexandra J., Eckle, Sidonia B. G., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y. W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie and McCluskey, James (2015). T cell activation by transitory neo-antigens derived from distinct microbial pathways. 8th International Workshop on Antigen Processing and Presentation, Philadelphia Pa, Jun 10-13, 2014. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD.
Yau, Mei Kwan, Suen, Jacky, Xu, Weijun, Lim, Junxian, Liu, Ligong, Adams, Mark, He, Yaowu, Hooper, John, Reid, Robert and Fairlie, David (2015). Potent small agonists of protease activated receptor 2. WASHINGTON: AMER CHEMICAL SOC.
Mak, Jeffrey, Corbett, Alexandra, Eckle, Sidonia, Birkinshaw, Richard, Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas, Strugnell, Richard, Van Sinderen, Douwe, Fairlie, David, Kjer-Nielsen, Lars, Rossjohn, Jamie and McCluskey, James (2015). T-cell antigen formed from distinct metabolic pathways. WASHINGTON: AMER CHEMICAL SOC.
Sakala, Isaac, Kjer-Nielsen, Lars, Eickhoff, Christopher, Wang, Xiaoli, Blazevic, Azra, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, McCluskey, James, Fremont, Daved, Hansen, Ted and Hoft, Daniel (2015). Antigen-specific MAIT cell subsets involved in TB immunity. Annual Meeting of the American-Association-of-Immunologists (IMMUNOLOGY), New Orleans La, May 08-12, 2015. BETHESDA: AMER ASSOC IMMUNOLOGISTS.
Sakala, Isaac G., Kjer-Nielsen, Lars, Eickhoff, Christopher S., Wang, Xiaoli, Liu, Ligong, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Hoft, Daniel F. and Hansen, Ted H. (2015). Tetramer identification of functional mouse mucosal associated invariant T (MAIT) cells. 8th International Workshop on Antigen Processing and Presentation, Philadelphia Pa, Jun 10-13, 2014. Oxford United Kingdom: Pergamon Press.
Sakala, Isaac, Kjer-Nielsen, Lars, Eickhoff, Christopher, Wang, Xiaoli, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Hoft, Daniel and Hansen, Ted (2014). Tetramer identification of functional mouse mucosal associated invariant T cells. BETHESDA: AMER ASSOC IMMUNOLOGISTS.
Fairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, 27-31 March 2011. Washington, DC, United States: American Chemical Society.
Yau, Annika M., Liu, Ligong, Reid, Robert C., Barry, Grant D., Suen, Jacky Y., Lohman, Rink-Jan, Le, Giang T., Cotterell, Adam and Fairlie, David P. (2011). Novel agonists and antagonists for protease activated receptor 2. National Meeting of the American Chemical Society (242nd, ACS, 2011), Denver, CO, U.S.A., 28 August-1 September 2011. WASHINGTON: AMER CHEMICAL SOC.
Dredge, K, Davis, K, Liu, L, Johnstone, K, Handley, P, Wimmer, N, Bytheway, I, Hammond, E, Li, CP, Rowley, J, Ferro, V and Gautam, A (2007). Heparan sulfate mimetics - potent angiogenesis inhibitors for cancer therapy. AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, San Francisco, CA, United States, 22-26 October 2007. Philadelphia, PA, United States: American Association for Cancer Research.
Patents
Ferro, V., Karoli, T., Liu, L., Handley, P.N., Johnstone, K.D., Wimmer, N. and Hammond, E.T. (2009). Novel sulfated oligosaccharide derivatives. WO/2009/049370.
Ferro, Vito, Fairweather, Jon, Karoli, Tomislav and Liu, Ligong (2005). Sulfated oligosaccharide derivatives. WO/2005/085264.
Don, Robert Hugh, Ferro, Vito, Bytheway, Ian, Cochran, Siska, Fairweather, Jon Krueger, Hammond, Edward Timothy, Karoli, Tomislav, Li, Cai Ping and Liu, Ligong (2005). Glycosaminoglycan (GAG) mimetics. WO/2005/061523.
Banwell, Martin Gerhardt, Liu, Ligong, Parish, Christopher Richard and Freeman, Craig Geoffrey (2003). Linked cyclitols and their polysulfated derivatives. WO/2003/004454.