Honorary Professor Jian Yang

Yang, J., Lee, (Sang) Hong, Goddard, M. E. and Visscher, Peter (2013). Genome-wide complex trait analysis (GCTA): methods, data analyses, and interpretations. Genome-Wide Association Studies and Genomic Prediction. (pp. 215-236) edited by Cedric Gondro, Julius van der Werf and Ben Hayes. New York, NY U.S.A.: Humana Press. doi: 10.1007/978-1-62703-447-0_9

Makowski, Carolina, van der Meer, Dennis, Dong, Weixiu, Wang, Hao, Wu, Yan, Zou, Jingjing, Liu, Cin, Rosenthal, Sara B., Hagler, Donald J., Fan, Chun Chieh, Kremen, William S., Andreassen, Ole A., Jernigan, Terry L., Dale, Anders M., Zhang, Kun, Visscher, Peter M., Yang, Jian and Chen, Chi-Hua (2022). Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases. Science, 375 (6580) A27, 522-528. doi: 10.1126/science.abe8457

Longchamps, R. J., Yang, S. Y., Castellani, C. A., Shi, W., Lane, J., Grove, M. L., Bartz, T. M., Sarnowski, C., Liu, C., Burrows, K., Guyatt, A. L., Gaunt, T. R., Kacprowski, T., Yang, J., De Jager, P. L., Yu, L., Bergman, A., Xia, R., Fornage, M., Feitosa, M. F., Wojczynski, M. K., Kraja, A. T., Province, M. A., Amin, N., Rivadeneira, F., Tiemeier, H., Uitterlinden, A. G., Broer, L., Van Meurs, J. B.J. ... Arking, D. E. (2022). Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Human Genetics, 141 (1), 127-146. doi: 10.1007/s00439-021-02394-w

Niemi, Mari E. K., Karjalainen, Juha, Liao, Rachel G., Neale, Benjamin M., Daly, Mark, Ganna, Andrea, Pathak, Gita A., Andrews, Shea J., Kanai, Masahiro, Veerapen, Kumar, Fernandez-Cadenas, Israel, Schulte, Eva C., Striano, Pasquale, Marttila, Minttu, Minica, Camelia, Marouli, Eirini, Karim, Mohd Anisul, Wendt, Frank R., Savage, Jeanne, Sloofman, Laura, Butler-Laporte, Guillaume, Kim, Han-Na, Kanoni, Stavroula, Okada, Yukinori, Byun, Jinyoung, Han, Younghun, Uddin, Mohammed Jashim, Smith, George Davey, Willer, Cristen J. ... Donohue, Chloe (2021). Mapping the human genetic architecture of COVID-19. Nature, 600 (7889), 472-477. doi: 10.1038/s41586-021-03767-x

Chen, Wenhan, Wu, Yang, Zheng, Zhili, Qi, Ting, Visscher, Peter M., Zhu, Zhihong and Yang, Jian (2021). Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors. Nature Communications, 12 (1) 7117, 7117. doi: 10.1038/s41467-021-27438-7

Fu, Yuanqing, Xu, Fengzhe, Jiang, Longda, Miao, Zelei, Liang, Xinxiu, Yang, Jian, Larsson, Susanna C. and Zheng, Ju-Sheng (2021). Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study. BMC Medicine, 19 (1) 171, 171. doi: 10.1186/s12916-021-02041-1

Jiang, Longda, Zheng, Zhili, Fang, Hailing and Yang, Jian (2021). A generalized linear mixed model association tool for biobank-scale data. Nature Genetics, 53 (11), 1616-1621. doi: 10.1038/s41588-021-00954-4

Ni, Guiyan, Zeng, Jian, Revez, Joana A., Wang, Ying, Zheng, Zhili, Ge, Tian, Restuadi, Restuadi, Kiewa, Jacqueline, Nyholt, Dale R., Coleman, Jonathan R.I., Smoller, Jordan W., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2021). A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts. Biological Psychiatry, 90 (9), 611-620. doi: 10.1016/j.biopsych.2021.04.018

Hemani, Gibran, Powell, Joseph E., Wang, Huanwei, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Goddard, Michael E., Gibson, Greg, Yang, Jian and Visscher, Peter M. (2021). Phantom epistasis between unlinked loci. Nature, 596 (7871), E1-E3. doi: 10.1038/s41586-021-03765-z

Yengo, Loic, Yang, Jian, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R. and Visscher, Peter M. (2021). Genomic partitioning of inbreeding depression in humans. American Journal of Human Genetics, 108 (8), 1488-1501. doi: 10.1016/j.ajhg.2021.06.005

Palmer, Rohan H. C., Benca-Bachman, Chelsie E., Huggett, Spencer B., Bubier, Jason A., McGeary, John E., Ramgiri, Nikhil, Srijeyanthan, Jenani, Yang, Jingjing, Visscher, Peter M., Yang, Jian, Knopik, Valerie S. and Chesler, Elissa J. (2021). Multi-omic and multi-species meta-analyses of nicotine consumption. Translational Psychiatry, 11 (1) 98, 98. doi: 10.1038/s41398-021-01231-y

Sun, Xiwei and Yang, Jian (2021). Towards the understanding of the genetics of somatic mutations. British Journal of Cancer, 125 (5), 627-628. doi: 10.1038/s41416-021-01369-y

Hivert, Valentin, Sidorenko, Julia, Rohart, Florian, Goddard, Michael E., Yang, Jian, Wray, Naomi R., Yengo, Loic and Visscher, Peter M. (2021). Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals. The American Journal of Human Genetics, 108 (5), 786-798. doi: 10.1016/j.ajhg.2021.02.014

Guo, Jing, Bakshi, Andrew, Wang, Ying, Jiang, Longda, Yengo, Loic, Goddard, Michael E., Visscher, Peter M. and Yang, Jian (2021). Quantifying genetic heterogeneity between continental populations for human height and body mass index. Scientific Reports, 11 (1) 5240, 1-9. doi: 10.1038/s41598-021-84739-z

Sun, Xiwei, Xue, Angli, Qi, Ting, Chen, Dan, Shi, Dandan, Wu, Yang, Zheng, Zhili, Zeng, Jian and Yang, Jian (2021). Tumor mutational burden is polygenic and genetically associated with complex traits and diseases. Cancer Research, 81 (5) canres.3459.2020, 12230-1239. doi: 10.1158/0008-5472.can-20-3459

Zeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2021). Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications, 12 (1) 1164, 1-12. doi: 10.1038/s41467-021-21446-3

Kemper, Kathryn E., Yengo, Loic, Zheng, Zhili, Abdellaoui, Abdel, Keller, Matthew C., Goddard, Michael E., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2021). Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals. Nature Communications, 12 (1) 1050, 1050. doi: 10.1038/s41467-021-21283-4

Adolphe, Christelle, Xue, Angli, Fard, Atefeh Taherian, Genovesi, Laura A., Yang, Jian and Wainwright, Brandon J. (2021). Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility. Genome Medicine, 13 (1) 19, 19. doi: 10.1186/s13073-021-00827-9

Kahali, Bratati, Chen, Yue, Feitosa, Mary F, Bielak, Lawrence F, Oconnell, Jeffrey R, Musani, Solomon K, Hegde, Yash, Chen, Yanhua, Stetson, L. C, Guo, Xiuqing, Fu, Yi-Ping, Smith, Albert Vernon, Ryan, Kathleen A, Eiriksdottir, Gudny, Cohain, Ariella T, Allison, Matthew, Bakshi, Andrew, Bowden, Donald W, Budoff, Matthew J, Carr, J. Jeffrey, Carskadon, Shannon, Chen, Yii-Der I, Correa, Adolfo, Crudup, Breland F, Du, Xiaomeng, Harris, Tamara B, Yang, Jian, Kardia, Sharon L. R, Launer, Lenore J ... Speliotes, Elizabeth K (2021). A noncoding variant near PPP1R3B promotes liver glycogen storage and MetS, but protects against myocardial Infarction. Journal of Clinical Endocrinology and Metabolism, 106 (2), 372-387. doi: 10.1210/clinem/dgaa855

Xue, Angli, Jiang, Longda, Zhu, Zhihong, Wray, Naomi R., Visscher, Peter M., Zeng, Jian and Yang, Jian (2021). Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications, 12 (1) 6450, 6450. doi: 10.1038/s41467-020-20237-6

Blokland, Gabriëlla A.M., Grove, Jakob, Chen, Chia-Yen, Cotsapas, Chris, Tobet, Stuart, Handa, Robert, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bergen, Sarah E., Bevilacqua, Elizabeth, Bigdeli, Tim B. ... iPSYCH (2021). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91 (1), 102-117. doi: 10.1016/j.biopsych.2021.02.972

Xu, Fengzhe, Fu, Yuanqing, Sun, Ting-Yu, Jiang, Zengliang, Miao, Zelei, Shuai, Menglei, Gou, Wanglong, Ling, Chu-Wen, Yang, Jian, Wang, Jun, Chen, Yu-Ming and Zheng, Ju-Sheng (2020). The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases. Microbiome, 8 (1) 145, 145. doi: 10.1186/s40168-020-00923-9

Folkersen, Lasse, Gustafsson, Stefan, Wang, Qin, Hansen, Daniel Hvidberg, Hedman, Åsa K., Schork, Andrew, Page, Karen, Zhernakova, Daria V., Wu, Yang, Peters, James, Eriksson, Niclas, Bergen, Sarah E., Boutin, Thibaud S., Bretherick, Andrew D., Enroth, Stefan, Kalnapenkis, Anette, Gådin, Jesper R., Suur, Bianca E., Chen, Yan, Matic, Ljubica, Gale, Jeremy D., Lee, Julie, Zhang, Weidong, Quazi, Amira, Ala-Korpela, Mika, Choi, Seung Hoan, Claringbould, Annique, Danesh, John, Davey Smith, George ... Mälarstig, Anders (2020). Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nature Metabolism, 2 (10), 1135-1148. doi: 10.1038/s42255-020-00287-2

Zhang, Qian, Sidorenko, Julia, Couvy-Duchesne, Baptiste, Marioni, Riccardo E., Wright, Margaret J., Goate, Alison M., Marcora, Edoardo, Huang, Kuan-lin, Porter, Tenielle, Laws, Simon M., Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Sachdev, Perminder S., Mather, Karen A., Armstrong, Nicola J., Thalamuthu, Anbupalam, Brodaty, Henry, Yengo, Loic, Yang, Jian, Wray, Naomi R., McRae, Allan F. and Visscher, Peter M. (2020). Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture. Nature Communications, 11 (1) 4799, 1-11. doi: 10.1038/s41467-020-18534-1

Wang, Ying, Guo, Jing, Ni, Guiyan, Yang, Jian, Visscher, Peter M. and Yengo, Loic (2020). Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations. Nature Communications, 11 (1) 3865, 3865. doi: 10.1038/s41467-020-17719-y

Couvy‐Duchesne, Baptiste, Strike, Lachlan T., Zhang, Futao, Holtz, Yan, Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Colliot, Olivier, Wright, Margaret J., Wray, Naomi R., Yang, Jian and Visscher, Peter M. (2020). A unified framework for association and prediction from vertex‐wise grey‐matter structure. Human Brain Mapping, 41 (14) hbm.25109, 4062-4076. doi: 10.1002/hbm.25109

Wu, Yang, Qi, Ting, Wang, Huanwei, Zhang, Futao, Zheng, Zhili, Phillips-Cremins, Jennifer E., Deary, Ian J., McRae, Allan F., Wray, Naomi R., Zeng, Jian and Yang, Jian (2020). Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data. Nature Communications, 11 (1) 2061, 1-12. doi: 10.1038/s41467-020-15587-0

Revez, Joana A., Lin, Tian, Qiao, Zhen, Xue, Angli, Holtz, Yan, Zhu, Zhihong, Zeng, Jian, Wang, Huanwei, Sidorenko, Julia, Kemper, Kathryn E., Vinkhuyzen, Anna A. E., Frater, Julanne, Eyles, Darryl, Burne, Thomas H. J., Mitchell, Brittany, Martin, Nicholas G., Zhu, Gu, Visscher, Peter M., Yang, Jian, Wray, Naomi R. and McGrath, John J. (2020). Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nature Communications, 11 (1) 1647, 1-12. doi: 10.1038/s41467-020-15421-7

Vallerga, Costanza L., Zhang, Futao, Fowdar, Javed, McRae, Allan F., Qi, Ting, Nabais, Marta F., Zhang, Qian, Kassam, Irfahan, Henders, Anjali K., Wallace, Leanne, Montgomery, Grant, Chuang, Yu-Hsuan, Horvath, Steve, Ritz, Beate, Halliday, Glenda, Hickie, Ian, Kwok, John B., Pearson, John, Pitcher, Toni, Kennedy, Martin, Bentley, Steven R., Silburn, Peter A., Yang, Jian, Wray, Naomi R., Lewis, Simon J. G., Anderson, Tim, Dalrymple-Alford, John, Mellick, George D., Visscher, Peter M. and Gratten, Jacob (2020). Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease. Nature Communications, 11 (1) 1238, 1238. doi: 10.1038/s41467-020-15065-7

Mortlock, Sally, Kendarsari, Raden I., Fung, Jenny N., Gibson, Greg, Yang, Fei, Restuadi, Restuadi, Girling, Jane E., Holdsworth-Carson, Sarah J., Teh, Wan Tinn, Lukowski, Samuel W., Healey, Martin, Qi, Ting, Rogers, Peter A. W., Yang, Jian, McKinnon, Brett and Montgomery, Grant W. (2020). Tissue specific regulation of transcription in endometrium and association with disease. Human Reproduction, 35 (2), 377-393. doi: 10.1093/humrep/dez279

Yang, Jian (2020). The SNP-based heritability - a commentary on Yang et al. (2010). Twin Research and Human Genetics, 23 (2), 118-119. doi: 10.1017/thg.2020.25

McCartney, Daniel L., Zhang, Futao, Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Boutin, Thibaud, Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Hayward, Caroline, Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Yang, Jian, Visscher, Peter M., McRae, Allan F. and Marioni, Riccardo E. (2019). An epigenome-wide association study of sex-specific chronological ageing. Genome Medicine, 12 (1) 1, 1. doi: 10.1186/s13073-019-0693-z

Xu, Jun, Falconer, Caitlin, Nguyen, Quan, Crawford, Joanna, McKinnon, Brett D., Mortlock, Sally, Senabouth, Anne, Andersen, Stacey, Chiu, Han Sheng, Jiang, Longda, Palpant, Nathan J., Yang, Jian, Mueller, Michael D., Hewitt, Alex W., Pébay, Alice, Montgomery, Grant W., Powell, Joseph E. and Coin, Lachlan J. M. (2019). Genotype-free demultiplexing of pooled single-cell RNA-seq. Genome Biology, 20 (1) 290, 290. doi: 10.1186/s13059-019-1852-7

Nalls, Mike A, Blauwendraat, Cornelis, Vallerga, Costanza L, Heilbron, Karl, Bandres-Ciga, Sara, Chang, Diana, Tan, Manuela, Kia, Demis A, Noyce, Alastair J, Xue, Angli, Bras, Jose, Young, Emily, von Coelln, Rainer, Simón-Sánchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Pihlstrøm, Lasse, Siitonen, Ari, Iwaki, Hirotaka, Leonard, Hampton, Faghri, Faraz, Gibbs, J Raphael, Hernandez, Dena G, Scholz, Sonja W, Botia, Juan A, Martinez, Maria, Corvol, Jean-Christophe, Lesage, Suzanne ... Zhang, Futao (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 18 (12), 1091-1102. doi: 10.1016/S1474-4422(19)30320-5

Jiang, Longda, Zheng, Zhili, Qi, Ting, Kemper, Kathryn E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2019). A resource-efficient tool for mixed model association analysis of large-scale data. Nature Genetics, 51 (12), 1749-1755. doi: 10.1038/s41588-019-0530-8

Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tõnu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2019). Improved polygenic prediction by Bayesian multiple regression on summary statistics. Nature Communications, 10 (1) 5086, 1-10. doi: 10.1038/s41467-019-12653-0

Deng, Lian, Zhang, Chao, Yuan, Kai, Gao, Yang, Pan, Yuwen, Ge, Xueling, He, Yaoxi, Yuan, Yuan, Lu, Yan, Zhang, Xiaoxi, Chen, Hao, Lou, Haiyi, Wang, Xiaoji, Lu, Dongsheng, Liu, Jiaojiao, Tian, Lei, Feng, Qidi, Khan, Asifullah, Yang, Yajun, Jin, Zi-Bing, Yang, Jian, Lu, Fan, Qu, Jia, Kang, Longli, Su, Bing and Xu, Shuhua (2019). Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders. National Science Review, 6 (6), 1201-1222. doi: 10.1093/nsr/nwz108

Andlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Stahl, Eli A, Breen, Gerome, Forstner, Andreas J, McQuillin, Andrew, Ripke, Stephan ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry, 26 (4), 1286-1298. doi: 10.1038/s41380-019-0558-2

Noyce, Alastair J., Bandres-Ciga, Sara, Kim, Jonggeol, Heilbron, Karl, Kia, Demis, Hemani, Gibran, Xue, Angli, Lawlor, Debbie A., Smith, George Davey, Duran, Raquel, Gan-Or, Ziv, Blauwendraat, Cornelis, Gibbs, J. Raphael, Hinds, David A., Yang, Jian, Visscher, Peter, Cuzick, Jack, Morris, Huw, Hardy, John, Wood, Nicholas W., Nalls, Mike A., Singleton, Andrew B., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre ... Wilson, Catherine H. (2019). The Parkinson's disease Mendelian randomization research portal. Movement Disorders, 34 (12) mds.27873, 1864-1872. doi: 10.1002/mds.27873

Abdellaoui, Abdel, Hugh-Jones, David, Yengo, Loic, Kemper, Kathryn E., Nivard, Michel G., Veul, Laura, Holtz, Yan, Zietsch, Brendan P., Frayling, Timothy M., Wray, Naomi R., Yang, Jian, Verweij, Karin J. H. and Visscher, Peter M. (2019). Genetic correlates of social stratification in Great Britain. Nature Human Behaviour, 3 (12), 1332-1342. doi: 10.1038/s41562-019-0757-5

Wang, Huanwei, Zhang, Futao, Zeng, Jian, Wu, Yang, Kemper, Kathryn E., Xue, Angli, Zhang, Min, Powell, Joseph E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Science Advances, 5 (8) eaaw3538, 1-12. doi: 10.1126/sciadv.aaw3538

Sidorenko, Julia, Kassam, Irfahan, Kemper, Kathryn E., Zeng, Jian, Lloyd-Jones, Luke R., Montgomery, Grant W., Gibson, Greg, Metspalu, Andres, Esko, Tonu, Yang, Jian, McRae, Allan F. and Visscher, Peter M. (2019). The effect of X-linked dosage compensation on complex trait variation. Nature Communications, 10 (1) 3009, 3009. doi: 10.1038/s41467-019-10598-y

Zeng, Biao, Lloyd-Jones, Luke R., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Franke, Lude, Vosa, Urmo, Claringbould, Annique, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E. and Gibson, Greg (2019). Comprehensive multiple eQTL detection and its application to GWAS interpretation. Genetics, 212 (3), 905-918. doi: 10.1534/genetics.119.302091

Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R. and Visscher, Peter M. (2019). Correction: GWAS on family history of Alzheimer’s disease. Translational Psychiatry, 9 (1) 161, 161. doi: 10.1038/s41398-019-0498-2

Zhang, Futao, Chen, Wenhan, Zhu, Zhihong, Zhang, Qian, Nabais, Marta F., Qi, Ting, Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F. and Yang, Jian (2019). OSCA: a tool for omic-data-based complex trait analysis. Genome Biology, 20 (1) 107, 107. doi: 10.1186/s13059-019-1718-z

Bond, Tom A., Karhunen, Ville, Wielscher, Matthias, Auvinen, Juha, Männikkö, Minna, Keinänen-Kiukaanniemi, Sirkka, Gunter, Marc J., Felix, Janine F., Prokopenko, Inga, Yang, Jian, Visscher, Peter M., Evans, David M, Sebert, Sylvain, Lewin, Alex, O’Reilly, Paul F., Lawlor, Debbie A. and Jarvelin, Marjo-Riitta (2019). Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts. International Journal of Epidemiology, 49 (1), 233-243. doi: 10.1093/ije/dyz095

Kassam, Irfahan, Wu, Yang, Yang, Jian, Visscher, Peter M. and McRae, Allan F. (2019). Tissue-specific sex-differences in human gene expression. Human Molecular Genetics, 28 (17), 2976-2986. doi: 10.1093/hmg/ddz090

Wu, Yeda, Byrne, Enda M., Zheng, Zhili, Kemper, Kathryn E., Yengo, Loic, Mallett, Andrew J., Yang, Jian, Visscher, Peter M. and Wray, Naomi R. (2019). Genome-wide association study of medication-use and associated disease in the UK Biobank. Nature Communications, 10 (1) 1891, 1891. doi: 10.1038/s41467-019-09572-5

Reynolds, Regina H., Botia, Juan, Nalls, Mike A., Hardy, John, Taliun, Sarah A. Gagliano, Ryten, Mina, Noyce, Alastair J., Nicolas, Aude, Cookson, Mark R., Bandres-Ciga, Sara, Gibbs, J. Raphael, Hernandez, Dena G., Singleton, Andrew B., Reed, Xylena, Leonard, Hampton, Blauwendraat, Cornelis, Faghri, Faraz, Bras, Jose, Guerreiro, Rita, Tucci, Arianna, Kia, Demis A., Houlden, Henry, Plun-Favreau, Helene, Mok, Kin Y., Wood, Nicholas W., Lovering, Ruth, R'Bibo, Lea, Rizig, Mie, Chelban, Viorica ... Pearson, John (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability. Npj Parkinsons Disease, 5 (1) 6, 6. doi: 10.1038/s41531-019-0076-6

Yang, Yongjie, van der Klaauw, Agatha A., Zhu, Liangru, Cacciottolo, Tessa M., He, Yanlin, Stadler, Lukas K. J., Wang, Chunmei, Xu, Pingwen, Saito, Kenji, Hinton, Antentor, Yan, Xiaofeng, Keogh, Julia M., Henning, Elana, Banton, Matthew C., Hendricks, Audrey E., Bochukova, Elena G., Mistry, Vanisha, Lawler, Katherine L., Liao, Lan, Xu, Jianming, O'Rahilly, Stephen, Tong, Qingchun, Barroso, Ines, O'Malley, Bert W., Farooqi, I. Sadaf, Xu, Yong, Balasubramanian, Senduran, Clapham, Peter, Coates, Guy ... Zhang, Weihua (2019). Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nature Communications, 10 (1) 1718. doi: 10.1038/s41467-019-08737-6

Marouli, Eirini, Del Greco, M. Fabiola, Astley, Christina M., Yang, Jian, Ahmad, Shafqat, Berndt, Sonja I., Caulfield, Mark J., Evangelou, Evangelos, McKnight, Barbara, Medina-Gomez, Carolina, van Vliet-Ostaptchouk, Jana V., Warren, Helen R., Zhu, Zhihong, Hirschhorn, Joel N., Loos, Ruth J. F., Kutalik, Zoltan and Deloukas, Panos (2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Communications Biology, 2 (1) 119, 119. doi: 10.1038/s42003-019-0361-2

Mortlock, Sally, Restuadi, Restuadi, Levien, Rupert, Girling, Jane E., Holdsworth-Carson, Sarah J., Healey, Martin, Zhu, Zhihong, Qi, Ting, Wu, Yang, Lukowski, Samuel W., Rogers, Peter A. W., Yang, Jian, McRae, Allan F., Fung, Jenny N. and Montgomery, Grant W. (2019). Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases. Clinical Epigenetics, 11 (1) 49, 49. doi: 10.1186/s13148-019-0648-7

Lakhani, Chirag M., Tierney, Braden T., Manrai, Arjun K., Yang, Jian, Visscher, Peter M. and Patel, Chirag J. (2019). Author correction: Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes. Nature Genetics, 51 (4), 764-765. doi: 10.1038/s41588-019-0377-z

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Vilhjalmsson, Bjarni J., Yang, Jian, Finucane, Hilary K., Gusev, Alexander, Lindstrom, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron, Hayeck, Tristan, Won, Hong-Hee, Kathiresan, Sekar, Pato, Michele, Pato, Carlos, Tamimi, Rulla, Stahl, Eli, Zaitlen, Noah, Pasaniuc, Bogdan, Belbin, Gillian, Kenny, Eimear E., Schierup, Mikkel H., De Jager, Philip, Patsopouos, Nikolaos A., Mc Carroll, Steve, Daly, Mark, Purce, Shaun, Chasman, Daniel, Neale, Benjamin ... Price, Alkes L. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics, 97 (4), 576-592. doi: 10.1016/j.ajhg.2015.09.001

The UK10K Consortium, Evans, David M., Kemp, John P., Visscher, Peter M. and Yang, Jian (2015). The UK10K project identifies rare variants in health and disease. Nature, 526 (7571), 82-89. doi: 10.1038/nature14962

Shah, Sonia, Bonder, Marc J., Marioni, Riccardo E., Zhu, Zhihong, McRae, Allan F., Zhernakova, Alexandra, Harris, Sarah E., Liewald, Dave, Henders, Anjali K., Mendelson, Michael M., Liu, Chunyu, Joehanes, Roby, Liang, Liming, Levy, Daniel, Martin, Nicholas G., Starr, John M., Wijmenga, Cisca, Wray, Naomi R., Yang, Jian, Montgomery, Grant W., Franke, Luke, Deary, Ian J., Visscher, Peter M. and BIOS Consortium (2015). Improving phenotypic prediction by combining genetic and epigenetic associations. American Journal of Human Genetics, 97 (1), 75-85. doi: 10.1016/j.ajhg.2015.05.014

Tropf, Felix C., Stulp, Gert, Barban, Nicola, Visscher, Peter M., Yang, Jian, Snieder, Harold and Mills, Melinda C. (2015). Human fertility, molecular genetics, and natural selection in modern societies. Plos One, 10 (6) e0126821, 1-14. doi: 10.1371/journal.pone.0126821

Thrift, Aaron P, Gong, Jian, Peters, Ulrike, Chang-Claude, Jenny, Rudolph, Anja, Slattery, Martha L, Chan, Andrew T, Esko, Tonu, Wood, Andrew R, Yang, Jian, Vedantam, Sailaja, Gustafsson, Stefan, Pers, Tune H., Baron, John A., Bezieau, Stephane, Kuery, Sebastien, Ogino, Shuji, Berndt, Sonja I, Casey, Graham, Haile, Robert W, Du, Mengmeng, Harrison, Tabitha A, Thornquist, Mark, Duggan, David J., Le Marchand, Loic, Lemire, Mathieu, Lindor, Noralane M, Seminara, Daniela, Song, Mingyang ... Campbell, Peter T (2015). Mendelian randomization study of height and risk of colorectal cancer. International Journal of Epidemiology, 44 (2) dyv082, 662-672. doi: 10.1093/ije/dyv082

Hayeck, Tristan J., Zaitlen, Noah A., Loh, Po-Ru, Vilhjalmsson, Bjarni, Pollack, Samuela, Gusev, Alexander, Yang, Jian, Chen, Guo-Bo, Goddard, Michael E., Visscher, Peter M., Patterson, Nick and Price, Alkes L. (2015). Mixed model with correction for case-control ascertainment increases association power. American Journal of Human Genetics, 96 (5), 720-730. doi: 10.1016/j.ajhg.2015.03.004

Taylor, Peter N., Porcu, Eleonora, Chew, Shelby, Campbell, Purdey J., Traglia, Michela, Brown, Suzanne J., Mullin, Benjamin H., Shihab, Hashem A., Min, Josine, Walter, Klaudia, Memari, Yasin, Huang, Jie, Barnes, Michael R., Beilby, John P., Charoen, Pimphen, Danecek, Petr, Dudbridge, Frank, Forgetta, Vincenzo, Greenwood, Celia, Grundberg, Elin, Johnson, Andrew D., Hui, Jennie, Lim, Ee M., McCarthy, Shane, Muddyman, Dawn, Panicker, Vijay, Perry, John R. B., Bell, Jordana T., Yuan, Wei ... Yang, Jian (2015). Whole-genome sequence-based analysis of thyroid function. Nature Communications, 6 (1) 5681, 5681.1-5681.10. doi: 10.1038/ncomms6681

Bulik-Sullivan, Brendan K., Loh, Po-Ru, Finucane, Hilary K., Ripke, Stephen, Yang, Jian, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson, Nick, Daly, Mark J., Price, Alkes L., Neale, Benjamin M., Nertney, Deborah A., Mowry, Bryan J. and Catts, Stanley V. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47 (3), 291-295. doi: 10.1038/ng.3211

Zhu, Zhihong, Bakshi, Andrew, Vinkhuyzen, Anna A. E., Hemani, Gibran, Lee, Sang Hong, Nolte, Ilja M., vanVliet-Ostaptchouk, Jana V., Snieder, Harold, Esko, Tonu, Milani, Lili, Magi, Reedik, Metspalu, Andres, Hill, William G., Weir, Bruce S., Goddard, Michael E., Visscher, Peter M. and Yang, Jian (2015). Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits. American Journal of Human Genetics, 96 (3), 377-385. doi: 10.1016/j.ajhg.2015.01.001

Hayat, Yousaf, Yang, Jian and Zhu, Jun (2015). Mixed model approaches for detecting influential observations in genetic data analysis. Pakistan Journal of Statistics, 31 (1), 121-134.

Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja, Gustafsson, Stefan, Esko, Tonu, Frayling, Tim, Speliotes, Elizabeth K., Boehnke, Michael, Raychaudhuri, Soumya, Fehrmann, Rudolf S. N., Hirschhorn, Joel N. and Franke, Lude (2015). Biological interpretation of genome-wide association studies using predicted gene functions. Nature Communications, 6 (Art No.: 5890) 5890, 5890-5890. doi: 10.1038/ncomms6890

Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tonu, Medland, Sarah E., Vinkhuyzen, Anna A. E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T., Domingue, Benjamin W., Hinds, David A., Johannesson, Magnus, Kiefer, Amy K., Laibson, David, Magnusson, Patrik K. E., Mountain, Joanna L., Oskarsson, Sven, Rostapshova, Olga, Teumer, Alexander, Tung, Joyce Y., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David and Koellinger, Philipp D. (2014). Replicability and robustness of genome-wide-association studies for behavioral traits. Psychological Science, 25 (11), 1975-1986. doi: 10.1177/0956797614545132

Hemani, Gibran, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Yang, Jian, Gibson, Greg, Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Visscher, Peter M. and Powell, Joseph E. (2014). Another explanation for apparent epistasis: reply. Nature, 514 (7520), E5-E6. doi: 10.1038/nature13692

Tada, Hayato, Won, Hong-Hee, Melander, Olle, Yang, Jian, Peloso, Gina M. and Kathiresan, Sekar (2014). Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease. Circulation-Cardiovascular Genetics, 7 (5), 583-587. doi: 10.1161/CIRCGENETICS.113.000420

Timpson, Nicholas J., Walter, Klaudia, Min, Josine L., Tachmazidou, Ioanna, Malerba, Giovanni, Shin, So-Youn, Chen, Lu, Futema, Marta, Southam, Lorraine, Iotchkova, Valentina, Cocca, Massimiliano, Huang, Jie, Memari, Yasin, McCarthy, Shane, Danecek, Petr, Muddyman, Dawn, Mangino, Massimo, Menni, Cristina, Perry, John R. B., Ring, Susan M., Gaye, Amadou, Dedoussis, George, Farmaki, Aliki-Eleni, Burton, Paul, Talmud, Philippa J., Gambaro, Giovanni, Spector, Tim D., Smith, George Davey, Durbin, Richard ... Yang, Jian (2014). A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nature Communications, 5 (1) 4871, 1-10. doi: 10.1038/ncomms5871

Robinson, E. B., Kirby, A., Ruparel, K., Yang, J., McGrath, L., Anttila, V., Neale, B. M., Merikangas, K., Lehner, T., Sleiman, P. M. A., Daly, M. J., Gur, R., Gur, R. and Hakonarson, H. (2014). The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Molecular Psychiatry, 20 (4), 454-458. doi: 10.1038/mp.2014.65

Jiang, Lei, Yin, Jian, Ye, Lingying, Yang, Jian, Hemani, Gibran, Liu, Ai-Jun, Zou, Hejian, He, Dongyi, Sun, Lingyun, Zeng, Xiaofeng, Li, Zhanguo, Zheng, Yi, Lin, Yiping, Liu, Yi, Fang, Yongfei, Xu, Jianhua, Li, Yinong, Dai, Shengming, Guan, Jianlong, Jiang, Lindi, Wei, Qianghua, Wang, Yi, Li, Yang, Huang, Cibo, Zuo, Xiaoxia, Liu, Yu, Wu, Xin, Zhang, Libin, Zhou, Ling ... Xu, Huji (2014). Erratum: Incorrect Institutional Affiliations of Authors in the Article by Jiang et al (Arthritis Rheumatol (2014)). Arthritis and Rheumatology, 66 (7), 1881-1881. doi: 10.1002/art.38728

Zhou, Kaixin, Donnelly, Lousie, Yang, Jian, Li, Miaoxin, Deshmukh, Harshal, Van Zuydam, Natalie, Ahlqvist, Emma, Spencer, Chris C., Groop, Leif, Morris, Andrew D., Colhoun, Helen M., Sham, Pak C., McCarthy, Mark I., Palmer, Colin N. A. and Pearson, Ewan R. (2014). Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis. The Lancet Diabetes and Endocrinology, 2 (6), 481-487. doi: 10.1016/S2213-8587(14)70050-6

Trzaskowski, M., Yang, J., Visscher, P. M. and Plomin, R. (2014). DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12. Molecular Psychiatry, 19 (3), 380-384. doi: 10.1038/mp.2012.191

Benyamin, B., St Pourcain, B., Davis, O. S., Davies, G., Hansell, N. K., Brion, M. J., Kirkpatrick, R. M., Cents, R. A. M., Franic, S., Miller, M. B., Haworth, C. M. A., Meaburn, E., Price, T. S., Evans, D. M., Timpson, N., Kemp, J., Ring, S., McArdle, W., Medland, S. E., Yang, J., Harris, S. E., Liewald, D. C., Scheet, P., Xiao, X., Hudziak, J. J., de Geus, E. J. C., Wellcome Trust Case Control Consortium 2 (WTCCC2), Jaddoe, V. W. V., Starr, J. M. ... Visscher, P. M. (2014). Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Molecular Psychiatry, 19 (2), 253-258. doi: 10.1038/mp.2012.184

Yang, Jian, Zaitlen, Noah A., Goddard, Michael E., Visscher, Peter M. and Price, Alkes L. (2014). Advantages and pitfalls in the application of mixed-model association methods. Nature Genetics, 46 (2), 100-106. doi: 10.1038/ng.2876

Jiang, Lei, Yin, Jian, Ye, Lingying, Yang, Jian, Hemani, Gibran, Liu, Ai-Jun, Zou, Hejian, He, Dongyi, Sun, Lingyun, Zeng, Xiaofeng, Li, Zhanguo, Zheng Yi, Lin, Yiping, Liu, Yi, Fang, Yongfei, Xu, Jianhua, Li, Yinong, Dai, Shengming, Guan, Jianlong, Jiang, Lindi, Wei, Qianghua, Wang, Yi, Li, Yang, Huang, Cibo, Zuo, Xiaoxia, Liu, Yu, Wu, Xin, Zhang, Libin, Zhou, Ling ... Xu, Huji (2014). Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans. Arthritis and Rheumatology, 66 (5), 1121-1132. doi: 10.1002/art.38353

Visscher, Peter M., Hemani, Gibran, Vinkhuyzen, Anna A. E., Chen, Guo-Bo, Lee, Sang Hong, Wray, Naomi R., Goddard, Michael E. and Yang, Jian (2014). Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples. PLoS Genetics, 10 (4) e1004269, e1004269.1-e1004269.10. doi: 10.1371/journal.pgen.1004269

Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tonu ... Brown, Matthew A. (2014). Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature, 506 (7488), 376-381. doi: 10.1038/nature12873

Hemani, Gibran, Yang, Jian, Vinkhuyzen, Anna, Powell, Joseph E., Willemsen, Gonneke, Hottenga, Jouke-Jan, Abdellaoui, Abdel, Mangino, Massimo, Valdes, Ana M., Medland, Sarah E., Madden, Pamela A., Heath, Andrew C., Henders, Anjali K., Nyholt, Dale R., de Geus, Eco J. C., Magnusson, Patrik K. E., Ingelsson, Erik, Montgomery, Grant W., Spector, Timothy D., Boomsma, Dorret I., Pedersen, Nancy L., Martin, Nicholas G. and Visscher, Peter M. (2013). Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs. American Journal of Human Genetics, 93 (5), 865-875. doi: 10.1016/j.ajhg.2013.10.005

Robinson, E. B., Howrigan, D., Yang, J., Ripke, S., Anttila, V., Duncan, L. E.,

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