Dr Stuart Kellie
Affiliate Principal Research Fellow
Institute for Molecular Bioscience
Researcher biography
I was an MRC Postdoctoral Research Fellow at University of Leicester, UK 1980-3, and a Postdoctoral Fellow at the Imperial Cancer Research Fund laboratories, London 1983-6. After a 6 month EMBO Fellowship to the Ludwig Institute for Cancer Research in Berne, Switzerland, in 1986 I was appointed Lecturer in Biochemistry at the Royal College Surgeons (Univ. London). In 1990 I was appointed Group Leader at Yamanouchi Research Institute, Oxford. In 2002 I joined The University of Queensland as Senior Lecturer, and promoted to Associate Professor in 2006. From 2005-8 I was Deputy CEO of the CRC for Chronic Inflammatory Diseases (CRC-CID).
I have international collaborations with Profs Chris Buckley and Steve Watson (University of Birmingham, UK); Prof Simon Lovestone and Dr. Richard Killick (Kings College London).
Book Chapters
Kellie, S. and Al-Mansour, Z. (2016). Overview of the immune system. In Skwarczynski, M and Toth, I (Ed.), Micro and nanotechnology in vaccine development (pp. 63-81) Oxford, United Kingdom: Elsevier. doi:10.1016/B978-0-323-39981-4.00004-X
Malik, Bilal, Fernandes, Cathy, Killick, Richard, Usardi, Alessia, Williamson, Ritchie, Kellie, Stuart, Anderton, Brian H. and Reynolds, C. Hugh (2014). Transcriptomic analysis of oligomeric amyloid-β treated primary cortical neurons reveals dysregulation of genes involved in the biosynthesis of steroids and cholesterol. In James V. Rogers (Ed.), Microarrays: principles, applications and technologies (pp. 269-295) New York, NY, United States: Nova Science Publishers.
Meng, Weining, Forwood, Jade K., Guncar, Gregor, Robin, Gautier, Cowieson, Nathan P., Listwan, Pawel, Mouradov, Dmitri, King, Gordon, Ross, lan L., Robinson, Jodie, Puri, Munish, Hill, Justine M., Kellie, Stuart, Huber, Thomas, Hume, David A., Martin, Jennifer L. and Kobe, Bostjan (2008). Overview of the pipeline for structural and functional characterization of macrophage proteins at the University of Queensland. In B. Kobe, M. Guss and T. L. Huber (Ed.), Structural proteomics: High-throughput methods (pp. 577-587) Totowa, NJ, United States: Humana Press.
Journal Articles
Zoccola, Emmanuelle, Kellie, Stuart and Barnes, Andrew C. (2017) Immune transcriptome reveals the mincle C-type lectin receptor acts as a partial replacement for TLR4 in lipopolysaccharide-mediated inflammatory response in barramundi (Lates calcarifer). Molecular Immunology, 83 33-45. doi:10.1016/j.molimm.2017.01.010
Ullah, M. Obayed, Sweet, Matthew J., Mansell, Ashley, Kellie, Stuart and Kobe, Bostjan (2016) TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target. Journal of Leukocyte Biology, 100 1: 27-45. doi:10.1189/jlb.2RI1115-531R
Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. W. M., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R., Lunnon, K., Kellie, S., Reynolds, C. H., Bazenet, C., Hodges, A., Brion, J.-P., Stephenson, J., Paul Simons, J. and Lovestone, S. (2014) Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry, 19 1: 88-98. doi:10.1038/mp.2012.163
Dave, Richa K., Naylor, Amy J., Young, Stephen P., Bayley, Rachel, Hardie, Debbie L., Haworth, Oliver, Rider, David A., Cook, Andrew D., Buckley, Christopher D. and Kellie, Stuart (2013) Differential expression of CD148 on leukocyte subsets in inflammatory arthritis. Arthritis Research and Therapy, 15 5: R108.1-R108.13. doi:10.1186/ar4288
Dave, Richa K., Dinger, Marcel E., Andrew, Megan, Askarian-Amiri, Marjan, Hume, David A. and Kellie, Stuart (2013) Regulated expression of PTPRJ/CD148 and an antisense long noncoding RNA in macrophages by proinflammatory stimuli. PLoS One, 8 6: e68306.1-e68306.13. doi:10.1371/journal.pone.0068306
Chen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013) The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 5: 774-784. doi:10.1107/S0907444913001558
Ve, Thomas, Gay, Nicholas J., Mansell, Ashley, Kobe, Bostjan and Kellie, Stuart (2012) Adaptors in toll-like receptor signaling and their potential as therapeutic targets. Current Drug Targets, 13 11: 1360-1374. doi:10.2174/138945012803530260
Malik, Bilal, Fernandes, Cathy, Killick, Richard, Wroe, Richard, Usardi, Alessia, Williamson, Ritchie, Kellie, Stuart, Anderton, Brian H. and Reynolds, C. Hugh (2012) Oligomeric amyloid-beta peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons. Neurochemistry International, 61 3: 321-333. doi:10.1016/j.neuint.2012.05.006
Smart, Chanel E., Askarian Amiri, Marjan E., Wronski, Ania, Dinger, Marcel E., Crawford, Joanna, Ovchinnikov, Dmitry A., Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Song, Sarah, Wiesner, Christiane, French, Juliet D., Dave, Richa K., da Silva, Leonard, Purdon, Amy, Andrew, Megan, Mattick, John S., Lakhani, Sunil R., Brown, Melissa A. and Kellie, Stuart (2012) Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors. PLoS One, 7 7: e40742.1-e40742.13. doi:10.1371/journal.pone.0040742
Chen, Kai-En, Richards, Ayanthi A., Arrifin, Juliana K., Ross, Ian L., Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer L. (2012) The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallographica Section D: Biological Crystallography, 68 6: 637-648. doi:10.1107/S0907444912006592
Valkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J., Mansell, Ashley, Gay, Nicholas J., Martin, Jennifer L. and Kobe, Bostjan (2011) Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proceedings of the National Academy of Sciences of the United States of America, 108 36: 14879-14884. doi:10.1073/pnas.1104780108
Scales, Timothy M. E., Derkinderen, Pascal, Leung, Kit-Yi, Byers, Helen L., Ward, MA, Price, Caroline, Bird, Ian N., Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Anderton, Brian H. and Reynolds, C. Hugh (2011) Tyrosine phosphorylation of Tau by the Src family kinases Lck and Fyn. Molecular Neurodegeneration, 6 1: 1-11. doi:10.1186/1750-1326-6-12
Van Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011) Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 1: e15723-1-e15723-13. doi:10.1371/journal.pone.0015723
Kirkby, Brenda, Roman, Noelia, Kobe, Bostjan, Kellie, Stuart and Forwood, Jade K. (2010) Functional and structural properties of mammalian acyl-coenzyme A thioesterases. Progress in Lipid Research, 49 4: 366-377. doi:10.1016/j.plipres.2010.04.001
Lattin, J. E., Greenwood, K. P., Daly, N. L., Kelly, G, Zidar, D. A., Clark, R. J., Thomas, W. G., Kellie, Stuart, Craik, D. J., Hume, D. A. and Sweet, M. J. (2009) Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival. Molecular Immunology, 47 2-3: 340-347. doi:10.1016/j.molimm.2009.09.012
Dave, R. K., Hume, D. A., Elsegood, C and Kellie, S (2009) CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages. Experimental Cell Research, 315 10: 1734-1744. doi:10.1016/j.yexcr.2009.02.023
Reynolds, C. Hugh, Garwood, Claire J., Wray, Selina, Price, Caroline, Kellie, Stuart, Perera, Timothy, Zvelebil, Marketa, Yang, Alice, Sheppard, Paul W., Varndell, Ian M., Hanger, Diane P. and Anderton, Brian H. (2008) Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase C gamma 1, Grb2, and Src family kinases. The Journal of Biological Chemistry, 283 26: 18177-18186. doi:10.1074/jbc.M709715200
Lattin, Jane E., Schroder, Kate, Su, Andrew I., Walker, John R., Zhang, Jie, Wiltshire, Tim, Saijo, Kaoru, Glass, Christopher K., Hume, David A., Kellie, Stuart and Sweet, Matthew J. (2008) Expression analysis of G Protein-coupled receptors in mouse macrophages. Immunome Research, 4 5: 5. doi:10.1186/1745-7580-4-5
Ovchinnikov, Dmitry A., van Zuylen, Wendy J. M., DeBats, Claire E. E., Alexander, Kylie A., Kellie, Stuart and Hume, David A. (2008) Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. Journal of Leukocyte Biology, 83 2: 430-433. doi:10.1189/jlb.0807585
Dhall, Girish, Finlay, Jonathan L., Dunkel, Ira J., Ettinger, Lawrence J., Kellie, Stewart J., Allen, Jeffrey C., Egeler, R. Maarten and Arceci, Robert J. (2008) Analysis of outcome for patients with mass lesions of the central nervous system due to langerhans cell histiocytosis treated with 2-chlorodeoxyadenosine. Pediatric Blood and Cancer, 50 1: 72-79. doi:10.1002/pbc.21225
Lattin, J., Zidar, D., Schroder, K., Kellie, S., Hume, D. and Sweet, M. (2007) G-protein-coupled receptor expression, function, and signaling in macrophages. Journal of Leukocyte Biology, 82 1: 16-32. doi:10.1189/jlb.0107051
Forwood, J., Thakur, A., Guncar, G., Marfori, M., Mouradov, D., Meng, W., Robinson, J., Huber, T., Kellie, S., Martin, J. L., Hume, D. and Kobe, B. (2007) Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proceedings of The National Academy of Sciences of The United States of America, 104 25: 10382-10387. doi:10.1073/pnas.0700974104
van Zuijlen, WJM, Cook, AD, Ovchinnikov, DA, Kellie, S and Hume, DA (2007) The role of schlafen in macrophages and inflammation. Inflammation Research, 56 S389-S389.
Puri, M., Robin, G., Cowieson, N., Forwood, J. K., Listwan, P., Hu, S. H., Guncar, G., Huber, T., Kellie, S., Hume, D. A., Kobe, B. and Martin, J. L. (2006) Focusing in on structural genomics: The University of Queensland structural biology pipeline. Biomolecular Engineering, 23 6: 281-289. doi:10.1016/j.bioeng.2006.09.002
Derkinderen, Pascal, Scales, Timothy M. E., Hanger, Diane P., Leung, Kit-Yi, Byers, Helen L., Ward, Malcolm A., Lenz, Christof, Price, Caroline, Bird, Ian N., Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Noble, Wendy, Van Etten, Richard A. and Leroy, Karelle (2005) Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase. Journal of Neuroscience, 25 28: 6584-6593. doi:10.1523/JNEUROSCI.1487-05.2005
Aagaard, A., Listwan, P., Cowieson, N. P., Huber, T. L., Ravasi, T., Wells, C. A., Flanagan, J. U., Kellie, S., Hume, D. A., Kobe, B. and Martin, J. L. (2005) An inflammatory role for the mammalian carboxypeptidase inhibitor latexin: Relationship to cystatins and the tumor suppressor TIG1. Structure, 13 2: 309-317. doi:10.1016/j.str.2004.12.013
Scaife, S., Brown, R., Kellie, S., Filer, A., Martin, S., Thomas, A.M.C., Bradfield, P. F., Amft, N., Salmon, M. and Buckley, C. D. (2004) Detection of differentially expressed genes in synovial fibroblasts by restriction fragment differential display. Rheumatology, 43 11: 1346-1352. doi:10.1093/rheumatology/keh347
Kellie, S., Craggs, G., Bird, I. N. and Jones, G. E. (2004) The tyrosine phosphatase DEP-1 induces cytoskeletal rearrangements, aberrant cell-substratum interactions and a reduction in cell proliferation. Journal of Cell Science, 117 4: 609-618. doi:10.1242/jcs.00879
Kellie, S. (2003) Protein tyrosine phosphatases: Potential roles in disease. Sigma Celltransmissions, 19 2: 3-8.
Lim, J., Lennard, A., Sheppard, P. and Kellie, S. (2002) Identification of residues which regulate activity of the STE20-related kinase hMINK. Biochemical and Biophysical Research Communications, 300 3: 694-698. doi:10.1016/S0006-291X(02)02909-1
Williamson, R., Scales, T., Clark, B. R., Gibb, G., Reynolds, C. H., Kellie, S., Bird, I. N., Varndell, I. M., Sheppard, P. W., Everall, I. and Anderton, B. H. (2002) Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: Involvement of src family protein kinases. Journal of Neuroscience, 22 1: 10-20.
Craggs, G., Finan, P. M., Lawson, D., Wingfield, J., Perera, T., Gadher, S., Totty, N. F. and Kellie, S. (2001) A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. Journal of Biological Chemistry, 276 32: 30552-30560. doi:10.1074/jbc.M103142200
Craggs, G. and Kellie, S. (2001) A functional nuclear localization sequence in the C-terminal domain of SHP-1. Journal of Biological Chemistry, 276 26: 23719-23725. doi:10.1074/jbc.M102846200
Murray, JT, Craggs, G, Wilson, L and Kellie, S (2000) Mechanism of phosphatidylinositol 3-kinase-dependent increases in BAC1.2F5 macrophage-like cell density in response to M-CSF: Phosphatidylinositol 3-kinase inhibitors increase the rate of apoptosis rather than inhibit DNA synthesis. Inflammation Research, 49 11: 610-618. doi:10.1007/s000110050638
Murray, J, Wilson, L and Kellie, S (2000) Phosphatidylinositol-3 ' kinase-dependent vesicle formation in macrophages in response to macrophage colony stimulating factor. Journal of Cell Science, 113 2: 337-348.
Wilson, L, Butcher, C, Finan, P and Kellie, S (1997) SH3 domain-mediated interactions involving the phox components of the NADPH oxidase. Inflammation Research, 46 7: 265-271. doi:10.1007/s000110050185
Kellie, Stuart (1996) The cytoskeleton and neoplastic transformation. Cytoskeleton: A Multi-Volume Treatise, 3 C: 133-158. doi:10.1016/S1874-6020(96)80007-3
Finan, PM, Soames, CJ, Wilson, L, Nelson, DL, Stewart, DM, Truong, O, Hsuan, JJ and Kellie, S (1996) Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains. Journal of Biological Chemistry, 271 42: 26291-26295. doi:10.1074/jbc.271.42.26291
Finan, P, Koga, H, Zvelebil, MJ, Waterfield, MD and Kellie, S (1996) The C-terminal SH3 domain of p67Ph(phox) binds its natural ligand in a reverse orientation. Journal of Molecular Biology, 261 2: 173-180. doi:10.1006/jmbi.1996.0450
Robinson, A, Gibbins, J, RodriguezLinares, B, Finan, PM, Wilson, L, Kellie, S, Findell, P and Watson, SP (1996) Characterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linking. Blood, 88 2: 522-530.
Finan, PM, Hall, A and Kellie, S (1996) Sam68 from an immortalised B-cell line associates with a subset of SH3 domains. Febs Letters, 389 2: 141-144. doi:10.1016/0014-5793(96)00552-2
Wilson, L, Carrier, MJ and Kellie, S (1995) Pp125(fak) Tyrosine Kinase-Activity Is Not Required for the Assembly of F-Actin Stress Fibers and Focal Adhesions in Cultured Mouse Aortic Smooth-Muscle Cells. Journal of Cell Science, 108 2381-2391.
Bennett, PA, Finan, PM, Dixon, RJ and Kellie, S (1995) Tyrosine Phosphatase Antagonist-Induced Activation of the Neutrophil Nadph Oxidase - a Possible Role for Protein-Kinase-C. Immunology, 85 2: 304-310.
Finan, Peter, Shimizu, Yazuaki, Gout, Ivan, Hsuan, Justin, Truong, Oanh, Butcher, Christopher, Bennett, Paul, Waterfield, Michael D. and Kellie, Stuart (1994) An SH3 domain and proline-rich sequence mediate an interaction between 2 components of the phagocyte NADPH oxidase complex. Journal of Biological Chemistry, 269 19: 13752-13755.
Bennett, PA, Dixon, RJ and Kellie, S (1993) The Phosphotyrosine Phosphatase Inhibitor Vanadyl Hydroperoxide Induces Morphological Alterations, Cytoskeletal Rearrangements and Increased Adhesiveness in Rat Neutrophil Leukocytes. Journal of Cell Science, 106 891-901.
Anand, R, Wilkinson, JM and Kellie, S (1993) Localization of Pp60(c-Src) to the Surface-Membrane of Human Platelets. Oncogene, 8 11: 3013-3020.
Murphy, CT, Kellie, S and Westwick, J (1993) Tyrosine-Kinase Activity in Rabbit Platelets Stimulated with Platelet-Activating-Factor - the Effect of Inhibiting Tyrosine Kinase with Genistein On Platelet-Signal-Molecule Elevation and Functional-Responses. European Journal of Biochemistry, 216 2: 639-651. doi:10.1111/j.1432-1033.1993.tb18184.x
Wilson, L., Butcher, C. J. and Kellie, S. (1993) Calcium Ionophore A23187 Induces Interleukin-8 Gene-Expression and Protein Secretion in Human Monocytic Cells. Febs Letters, 325 3: 295-298. doi:10.1016/0014-5793(93)81092-E
Kellie, S., Horvath, A. R., Felice, G., Anand, R., Murphy, C. and Westwick, J. (1993) The interaction of the tyrosine kinase pp60src with membrane and cytoskeletal components. Symposia of the Society for Experimental Biology, 47 267-282.
Tanowitz, HB, Gumprecht, JP, Spurr, D, Calderon, TM, Ventura, MC, Raventossuarez, C, Kellie, S, Factor, SM, Hatcher, VB, Wittner, M and Berman, JW (1992) Cytokine Gene-Expression of Endothelial-Cells Infected with Trypanosoma-Cruzi. Journal of Infectious Diseases, 166 3: 598-603. doi:10.1093/infdis/166.3.598
Horvath, AR, Muszbek, L and Kellie, S (1992) Translocation of Pp60c-Src to the Cytoskeleton During Platelet-Aggregation. Embo Journal, 11 3: 855-861.
Murphy, CT, Elmore, M, Kellie, S and Westwick, J (1991) Comparison of the Role of Protein-Kinase-C in Platelet Functional-Responses Induced by 3 Different Mechanisms, Paf, Ionomycin and Arachidonic-Acid. Biochimica Et Biophysica Acta, 1133 1: 46-54. doi:10.1016/0167-4889(91)90240-X
Horvath, AR, Kiss, Z, Anand, R and Kellie, S (1991) Association of Pp60c-Src with the Cytoskeleton Upon Platelet Activation. Biochemical Society Transactions, 19 4: 1150-1154. doi:10.1042/bst0191150
Murphy, CT, Elmore, M, Kellie, S and Westwick, J (1991) The Relationship Between Cytosolic Ca2+, Sn-1,2-Diacylglycerol and Inositol 1,4,5-Trisphosphate Elevation in Platelet-Activating-Factor-Stimulated Rabbit Platelets - Influence of Protein-Kinase-C On Production of Signal Molecules. Biochemical Journal, 278 255-261. doi:10.1042/bj2780255
Kellie, S, Horvath, AR and Elmore, MA (1991) Cytoskeletal Targets for Oncogenic Tyrosine Kinases. Journal of Cell Science, 99 207-211.
Nermut, MV, Eason, P, Hirst, Ema and Kellie, S (1991) Cell Substratum Adhesions in Rsv-Transformed Rat Fibroblasts. Experimental Cell Research, 193 2: 382-397. doi:10.1016/0014-4827(91)90111-7
Horvath, AR and Kellie, S (1990) Regulation of Integrin Mobility and Cytoskeletal Association in Normal and Rsv-Transformed Chick-Embryo Fibroblasts. Journal of Cell Science, 97 307-315.
Horvath, AR, Elmore, MA and Kellie, S (1990) Differential Tyrosine-Specific Phosphorylation of Integrin in Rous-Sarcoma Virus-Transformed Cells with Differing Transformed Phenotypes. Oncogene, 5 9: 1349-1357.
Elmore, MA, Anand, R, Horvath, AR and Kellie, S (1990) Tyrosine-Specific Phosphorylation of Gpiiia in Platelet Membranes. Febs Letters, 269 2: 283-287. doi:10.1016/0014-5793(90)81177-P
Felice, GR, Eason, P, Nermut, MV and Kellie, S (1990) Pp60v-Src Association with the Cytoskeleton Induces Actin Reorganization Without Affecting Polymerization Status. European Journal of Cell Biology, 52 1: 47-59.
Kellie, S (1988) Cellular-Transformation, Tyrosine Kinase Oncogenes, and the Cellular Adhesion Plaque. Bioessays, 8 1: 25-30. doi:10.1002/bies.950080107
Tones, MA, Kellie, S and Hawthorne, JN (1987) Elevated Phosphatidylinositol Kinase-Activity in Rous-Sarcoma Virus-Transformed Cells - Lack of Evidence for Enzyme Translocation. Biochimica Et Biophysica Acta, 931 2: 165-169. doi:10.1016/0167-4889(87)90202-3
Kellie, S, Wigglesworth, NM, Patel, B, Holme, TC, Critchley, DR and Wyke, JA (1987) Membrane and Cytoskeletal Changes in Cells After Transformation by Rous-Sarcoma Virus. Biochemical Society Transactions, 15 5: 791-794. doi:10.1042/bst0150791
Nicol, A, Kellie, S and Nermut, MV (1987) Ultrastructural-Localization of Vinculin in Fibroblast Ventral Membranes. Cell Biology International, 11 3: 257-257. doi:10.1016/0309-1651(87)90071-3
Kellie, S and Wigglesworth, NM (1987) The Cytoskeletal Protein Vinculin Is Acylated by Myristic Acid. Febs Letters, 213 2: 428-432. doi:10.1016/0014-5793(87)81536-3
Kellie, S and Wigglesworth, NM (1987) The Cytoskeletal Protein Vinculin Is Acylated by Myristic Acid. FEBS Letters (Federation of European Biochemical Socities), 213 2: 428-432. doi:10.1016/0014-5793(87)81536-3
Kellie, S, Patel, B, Wigglesworth, NM, Critchley, DR and Wyke, JA (1986) The Use of Rous-Sarcoma Virus Transformation Mutants with Differing Tyrosine Kinase-Activities to Study the Relationships Between Vinculin Phosphorylation, Pp60V-Src Location and Adhesion Plaque Integrity. Experimental Cell Research, 165 1: 216-228. doi:10.1016/0014-4827(86)90546-X
Kellie, S, Patel, B, Mitchell, A, Critchley, DR, Wigglesworth, NM and Wyke, JA (1986) Comparison of the Relative Importance of Tyrosine-Specific Vinculin Phosphorylation and the Loss of Surface-Associated Fibronectin in the Morphology of Cells Transformed by Rous-Sarcoma Virus. Journal of Cell Science, 82 129-142.
Stoker, Andrew W., Kellie, Stuart and Wyke, John A. (1986) Intracellular-Localization and Processing of Pp60v-Src Proteins Expressed by 2 Distinct Temperature-Sensitive Mutants of Rous-Sarcoma Virus. Journal of Virology, 58 3: 876-883.
Holme, T. C., Kellie, S., Wyke, J. A. and Crawford, N. (1986) Effect of transformation by Rous sarcoma virus on the character and distribution of actin in Rat-1 fibroblasts: a biochemical and microscopical study. British Journal of Cancer, 53 4: 465-476. doi:10.1038/bjc.1986.74
Whyte, A, Ockleford, CD, Wooding, Fbp, Hamon, M, Allen, WR and Kellie, S (1986) Characteristics of Cells Derived From the Girdle Region of the Preimplantation Blastocyst of the Donkey. Cell and Tissue Research, 246 2: 343-352. doi:10.1007/BF00215896
Kellie, S, Holme, TC and Bissell, MJ (1985) Interaction of Tumor Promoters with Epithelial-Cells in Culture - An Immunofluorescence Study. Experimental Cell Research, 160 2: 259-274. doi:10.1016/0014-4827(85)90174-0
Kellie, S., Patel, B., Pierce, E. J. and Critchley, D. R. (1983) Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actinin. Journal of Cell Biology, 97 2: 447-454. doi:10.1083/jcb.97.2.447
Critchley, D. R., Kellie, S., Streuli, C. H., Patel, B., Ansell, S. and Pierce, E. (1982) The use of cholera toxin as a probe to study the organisation of ganglioside GM1 in membranes. Progress in clinical and biological research, 102 pt A 397-407.
Perkins, RM, Kellie, S, Patel, B and Critchley, DR (1982) Gangliosides as Receptors for Fibronectin - Comparison of Cell Spreading On a Ganglioside-Specific Ligand with That On Fibronectin. Experimental Cell Research, 141 2: 231-243. doi:10.1016/0014-4827(82)90211-7
Critchley, DR, Streuli, CH, Kellie, S, Ansell, S and Patel, B (1982) Characterization of the Cholera-Toxin Receptor On Balb/c 3t3 Cells as a Ganglioside Similar To, or Identical With, Ganglioside Gm1 - No Evidence for Galactoproteins with Receptor Activity. Biochemical Journal, 204 1: 209-219. doi:10.1042/bj2040209
Kellie, S and Evans, CW (1981) Changes in Lymphocyte Adhesiveness During Contact Sensitization. British Journal of Experimental Pathology, 62 2: 158-164.
Kellie, S, Evans, CW and Kemp, GD (1980) The Effects of Serum-Proteins On the Adhesion of Lymphocytes. Cell Biology International Reports, 4 8: 777-777. doi:10.1016/0309-1651(80)90130-7
Conference Papers
Kulis, C., Bourne, G., Kellie, S. and Smythe, M. (2010). Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domain. In: Abstracts of EPS 2010: The 31st European Peptide Symposium. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, (103-103). 5-9 September 2010. doi:10.1002/psc.1303
Van Zuiiien, Wim, Schroder, K, Garceau, V, Sweet, MJ, Kellie, S and Hume, DA (2008). Expression and function of Schlafen-4 in macrophage biology and inflammation. In: Cytokine. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, Montreal Canada, (246-246). Oct 12-16, 2008. doi:10.1016/j.cyto.2008.07.081
Kellie, SJ (2005). Overview and critique of clinical trials in CNS nongerminomatous germ cell tumors: Balancing survival against acute toxicities and late effects of treatment. In: Neuro-Oncology. 2nd International Symposium on Central Nervous System Germ Cell Tumors, Los Angeles Ca, (526-527). Nov 18-21, 2005.
Dave, R., Wilson, T., Cook, A., Vlahos, R., Hume, D. and Kellie, S. (2005). Investigation into the role of protein tyrosine phosphatase DEP-1 in macrophage function. In: 38th Annual Meeting of the Society-for-Leukocyte-Biology, Oxford, United Kingdom, (40-40). 21-24 September 2005.
Lattin, Jane E., Blomberg, Lovisa M., Daly, Norelle L., Craik, David J., Robinson, Jodie A., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2005). Beta-arrestin expression and function in macrophages. In: Inflammation 2005: Book of Abstracts. 7th World Congress on Inflammation: Inflammation 2005: Inflammation, the Key to much pathology, Melbourne, Australia, (S157-S158). 20 - 24 August 2005.
Noble, WJ, Derkinderen, P, Scales, T, Price, C, Bird, IN, Kellie, S, Varndell, IM and Sheppard, PW (2004). The microtubule-associated protein tau is phosphorylated on tyrosine 394. In: Neurobiology of Aging. 9th International Conference on Alzheimers Disease and Related Disorders, Philadelphia Pa, (S419-S419). Jul 17-22, 2004. doi:10.1016/S0197-4580(04)81376-9
Kellie, S., Chang, M-K., Craggs, G. and Jones, G. (2003). Expression of the tyrosine phosphatase DEP-1 (CD148) results in a reduction in proliferation and cytoskeletal changes. In: International Society for Interferon and Cytokine Research. International Society for Interferon and Cytokine Research, Cairns, (Poster). 26-30 Oct, 2003.
Scales, TME, Williamson, R, Anderton, BH, Reynolds, CH, Price, C, Kellie, S, Bird, IN, Leung, KY, Byers, HL, Ward, MA, Varndell, IM and Sheppard, PW (2002). Tyrosine phosphorylation of specific sites on tau by src family kinases. In: Neurobiology of Aging. , , (S500-S501). .
Reynolds, H, Williamson, R, Anderton, B, Price, C, Kellie, S and Zvelebil, M (2002). Tau binds to phosphatidylinositol-3-kinase, GRB2 phospholipase C gamma-1 and SRC-family kinases through SH3 domain. In: Neurobiology of Aging. , , (S266-S266). .
Murray, J, Kellie, S and Wilson, L (1997). Role of phosphatidylinositol 3-kinase in vesicle trafficking and proliferation in a colony stimulating factor-1-dependent mouse macrophage cell line.. In: Molecular Biology of the Cell. , , (760-760). .
Finan, PM, Soames, CJ, Stewart, DM, Nelson, DL and Kellie, S (1996). Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected SH3 domains. In: Molecular Biology of the Cell. , , (1989-1989). .
Kellie, S, Horvath, AR, Felice, G, Anand, R, Murphy, C and Westwick, J (1993). The Interaction of the Tyrosine Kinase Pp60(src) with Membrane and Cytoskeletal Components. In: Jones, G, Wigley, C and Warn, R, Cell Behaviour : Adhesion and Motility. Joint Meeting of the Soc-for-Experimental-Biology / British-Soc-for-Cell-Biology, Bath England, (267-282). Sep 28-Oct 01, 1992.
Grundy, JE, Roy, DM, Bowen, EF and Kellie, SM (1991). Transformation-Like Changes in the Cytoskeleton and Extracellular-Matrix in Cells Infected with Cytomegalovirus. In: Journal of Muscle Research and Cell Motility. , , (489-489). .
Kellie, S, Horvath, AR, Elmore, MA, Felice, G and Anand, R (1991). Membrane-Cytoskeletal Targets for Tyrosine Kinases. In: REID, E, COOK, GMW and LUZIO, JP, Cell Signalling : Experimental Strategies. 12Th International Subcellular Methodology Forum On Cell Signalling Experimental Strategies, Guildford England, (333-340). Sep 04-07, 1990.
Murphy, CT, Elmore, MA, Kellie, S and Westwick, J (1990). Characterization of Platelet Activating Factor Induced Inositol (1,4,5)-Trisphosphate Production in Platelets - Modulation by Protein-Kinase-C. In: European Journal of Pharmacology. , , (636-637). . doi:10.1016/0014-2999(90)93562-5
Felice, G, Horvath, AR and Kellie, S (1990). Tyrosine Kinase-Activities and Neoplastic Transformation. In: Biochemical Society Transactions. 631st Meeting of the Biochemical Soc : Development of Mixed-Function Oxidases, Guildford England, (69-72). Jul 12-14, 1989. doi:10.1042/bst0180069
KELLIE, S and WIGGLESWORTH, NM (1987). THE CYTOSKELETAL PROTEIN VINCULIN IS ACYLATED BY MYRISTIC ACID. In: , , (224-224). . doi:10.1016/0309-1651(87)90038-5
Kellie, S, Critchley, DR, Patel, B and Pierce, EJ (1982). Co-Distribution of Alpha-Actinin with a Capped Cell-Surface Glycolipid. In: Journal of Muscle Research and Cell Motility. , , (491-491). .
Evans, CW and Kellie, S (1981). Adhesiveness of Lymphocytes to Glass Substrates. In: Journal of Physiology-London. , , (P10-P11). .
Kellie, S and Evans, CW (1981). Changes in Lymphocyte Adhesiveness Associated with Mitogenic Stimulation. In: Journal of Anatomy. , , (465-466). .
Kellie, S and Lackie, JM (1978). Adhesion of Rabbit Blood and Peritoneal Polymorphonuclear Neutrophil Leukocytes to Glass. In: Journal of Anatomy. , , (418-419). .