Systems Genomics
We develop insights into the underlying biological mechanisms of human variation
Our research uses multiple layers of ‘omics data to investigate the regulation of the genome and its effect on human complex trait variation.
Our approach
By combining genetic analyses of complex traits and disease in large cohorts with ‘omics data (including DNA methlyation and gene-expression), we develop insights into the underlying biological mechanisms of human variation.
We approach this problem through the development and application of statistical and computational approaches to the analysis of high dimensional genomic data.
Research areas
Statistical methods for 'omics data
- Statistical models of biological processes
- Integrating 'omics data for phenotype prediction
Variation in molecular phenotypes
- Genetic control of 'omics data
- Environmental influences on genomic regulation
Human phenotypic variation
- Molecular basis of phenotypic variation
- Sex differences in genomic regulation
Publications
Group leader
Dr Allan McRae
Group Leader, Systems Genomics
Our Team
Research excellence
$1.3 billion+ commercial investment attracted to IMB research
1454 international collaborators
385 original publications in 2020
$28M in research funding last calendar year
20%+ of patent families at UQ are derived from IMB research
100% of donations go to the cause
Help us shape the future
Stories
- 5 November 2018Your NDA code that tells your body what size to grow in is similar to your biological parents’ code on what size to grow in.
- 19 October 2018Good and bad bacteria are everywhere, including on and in our bodies. Dr Mark Blaskovich explains how disease-causing bacteria enter our body and how we fight them off.
- 25 September 2018Q&A with Bruce Wyse, IMB Deputy Director Operations
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