Systems Genomics

We develop insights into the underlying biological mechanisms of human variation

 

Our research uses multiple layers of ‘omics data to investigate the regulation of the genome and its effect on human complex trait variation.
 

Our approach

By combining genetic analyses of complex traits and disease in large cohorts with ‘omics data (including DNA methlyation and gene-expression), we develop insights into the underlying biological mechanisms of human variation.

We approach this problem through the development and application of statistical and computational approaches to the analysis of high dimensional genomic data.

Research areas

Statistical methods for 'omics data

  • Statistical models of biological processes
  • Integrating 'omics data for phenotype prediction

Variation in molecular phenotypes

  • Genetic control of 'omics data
  • Environmental influences on genomic regulation

Human phenotypic variation

  • Molecular basis of phenotypic variation
  • Sex differences in genomic regulation

Publications

Brain Caudate basal ganglia

 

Group leader

Dr Allan McRae

Dr Allan McRae

Group Leader, Systems Genomics

  a.mcrae@imb.uq.edu.au
  UQ Researcher Profile

Our Team

Group Leader

Students

Research excellence

$1.3 billion+ commercial investment attracted to IMB research
1454 international collaborators
 
~385 original publications last calendar year
 
$28M in research funding last calendar year
 
20%+ of patent families at UQ are derived from IMB research
100% of donations go to the cause
 

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